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Image Unavailable-BOSSBS-11997R-CY7

Anti-DDAH1 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-11997R-CY7)
Supplier: Bioss
Description: DDAH, a dimethylarginine dimethylaminohydrolase, hydrolyzes dimethyl arginine (ADMA) and monomethyl arginine (MMA), both inhibitors of nitric oxide synthases, and may be involved in in-vivo modulation of nitric oxide production (1,2). Impairment of DDAH causes ADMA accumulation and a reduction in cGMP generation (3). DDAH II, the predominant DDAH isoform in endothelial cells, facilitates the induction of nitric oxide synthesis by all-trans-Retinoic acid (atRA) (4). DDAH proteins are highly expressed in colon, kidney, stomach and liver tissues (1).
UOM: 1 * 100 µl
Image Unavailable-PROOBP544

trans-Platin

Catalog Number: (PROOBP544)
Supplier: LGC Standards PROMOCHEM
Description: trans-Platin
UOM: 1 * 25 mg
Image Unavailable-ENZOADIVAPSV065E

Anti-STX2 Rabbit Polyclonal Antibody

Catalog Number: (ENZOADIVAPSV065E)
Supplier: ENZO LIFE SCIENCES
Description: Syntaxins are type II integral membrane proteins localized to membranes that regulate vesicle transport, protein maturation, and exocytosis. Syntaxin 1A resides in the nerve terminals of sensory neurons and nerve fibers reaching small blood vessels. Syntaxin 2 localizes to the apical plasma membrane and regulates epithelial-mesenchymal interactions. Syntaxin 6 is primarily localized to the trans-Golgi network, and partially co-localizes with AP-1 on clathrin-coated membranes. Syntaxin 13 is ubiquitously expressed and localizes to the tubular early and recycling endosomes, as well as endosomal vacuoles.
UOM: 1 * 100 µG
Image Unavailable-BOSSBS-13178R

Anti-FKBP25 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-13178R)
Supplier: Bioss
Description: FKBP25 is a member of the immunophilin protein family. The immunophilins are a highly conserved family of cis-trans peptidyl-prolyl isomerases that bind to and mediate the effects of immunosuppressive drugs, such as cyclosporin, FK506 and rapamycin. They inhibit T-cell proliferation by interrupting two specific cytoplasmic signal transmission pathways. FKBP25 is localized in the nucleus and is expressed in the brain, testis, ovary, and spleen. It may influence immunoregulation and cerebellum development, as well as protein folding and trafficking in neurons. FKBP25 associates with transcriptional repressor protein YY1 and histone deaceltylases, HDAC1 and HDAC2. FKBP25 may contain several casein kinase II phosphorylation sites, which are believed to be important for cell growth regulation.
UOM: 1 * 100 µl
Image Unavailable-EDQMY0001018

Organic reference standards, cisplatins, Ph. Eur.

Catalog Number: (EDQMY0001018)
Supplier: EDQM
Description: Organic Standard, Cisplatin impurity A, trans-diamminedichloroplatinum(II) (transplatin), Ph. Eur. standard
UOM: 1 * 15 mg
Image Unavailable-ENZOBMLEI1550100

D-erythro-Sphingosine ≥98% (by TLC)

Catalog Number: (ENZOBMLEI1550100)
Supplier: ENZO LIFE SCIENCES
Description: Common component of cell membranes, often as phosphatidyl conjugates. Is a potent (IC50=1-3 µM) and selective inhibitor of protein kinase C. Inhibition is competitive with diacylglycerol, phorbol dibutyrate and Ca2+ and it also inhibits PKC activation by other lipids. It acts on an equimolar basis with 1,2-dioleoylglycerol and does not affect other kinases such as MLCK and PKA. It is active in intact cells and has been identified as an endogenous constituent in HL-60 cells, neutrophils, rat liver, and brain and mouse tissues. Other activities include inhibition of phosphatidate phosphohydrolase, Na+,K+-ATPase, CTP:phosphocholine cytidylyltransferase, calmodulin-dependent enzymes, binding of factor VII to tissue factor, binding of thyrotropin releasing hormone to its receptor and activation of EGF receptor kinase, phospholipase D and casein kinase II.
UOM: 1 * 100 mg
Image Unavailable-USBI042683

Anti-TCEA3 Rabbit Polyclonal Antibody

Catalog Number: (USBI042683)
Supplier: US Biological
Description: Anti-TCEA3 Rabbit Polyclonal Antibody
UOM: 1 * 200 µl
Image Unavailable-USBI042684

Anti-TCEAL1 Rabbit Polyclonal Antibody

Catalog Number: (USBI042684)
Supplier: US Biological
Description: Anti-TCEAL1 Rabbit Polyclonal Antibody
UOM: 1 * 200 µl
Image Unavailable-USBI042683-BIOTIN

Anti-TCEA3 Rabbit Polyclonal Antibody (Biotin)

Catalog Number: (USBI042683-BIOTIN)
Supplier: US Biological
Description: Anti-TCEA3 Rabbit Polyclonal Antibody (Biotin)
UOM: 1 * 200 µl
Product Image-ACRO197320010

Bis(triphenylphosphine)palladium(II) chloride (15% Pd) for analysis

Supplier: Thermo Fisher Scientific
Description: Bis(triphenylphosphine)palladium(II) chloride (15% Pd) for analysis

MSDS

Image Unavailable-688000-5

Y-27632, Millipore®

Supplier: Merck Millipore (Calbiochem‎)
Description: A highly potent, cell-permeable, reversible, and selective inhibitor of Rho-associated protein kinases (Ki = 140 nm for p160ROCK). Also inhibits ROCK-II with equal potency. Also acts as a potent inhibitor of agonist-induced Ca<sup>2+</sup> sensitization of myosin phosphorylation and smooth muscle contraction.

Image Unavailable-PRSI91-840

Human recombinant Carboxypeptidase E (from Cells)

Catalog Number: (PRSI91-840)
Supplier: ProSci Inc.
Description: The active form of CPE cleaves C-terminal amino acid residues of the peptide, and is thus involved in the biosynthesis of peptide hormones and neurotransmitters including insulin, enkephalin, etc. It is thought that membrane-associated CPE acts as a sorting receptor for targeting regulated secretory proteins which are mostly prohormones and neuropeptides in the trans-Golgi network of the pituitary and in secretory granules into the secretory pathway. Defects in this protein are implicated in type II diabetes due to impaired glucose clearance and insulin resistance.
UOM: 1 * 50 µG
Product Image-PRSI7151

Anti-MECR Rabbit Polyclonal Antibody

Catalog Number: (PRSI7151)
Supplier: ProSci Inc.
Description: MECR Antibody: The mitochondrial trans-2-enoyl-CoA reductase (MECR), was initially identified as nuclear receptor-binding factor 1 (NRBF1), which can interact with a multitude of nuclear hormone receptors in the presence of the respective ligands. MECR has been shown to be part of the mitochondrial fatty acid synthesis (FAS II) system and to catalyze the NAPDH-dependent reduction of 2-enoyl thioesters, generating saturated acyl-groups. Overexpression of this gene in transgenic mice can lead to cardiac abnormalities, suggesting that inappropriate expression of genes of FAS II can result in the development of hereditary cardiomyopathy.
UOM: 1 * 100 µG
Product Image-PRSI4011

Anti-TRBP1 Rabbit Polyclonal Antibody

Catalog Number: (PRSI4011)
Supplier: ProSci Inc.
Description: TRBP1 Antibody: The human trans-activation response (TAR) RNA binding protein 1 (TRBP1) was initially identified as a protein that binds to the HIV-1 TAR RNA and activates the long terminal repeat (LTR) expression in the absence and presence of the viral trans-activator Tat. This binding is enhanced by the presence of co-factors such as elongation factor 1 alpha (EF-1 alpha ), polypyrimidine tract-binding protein (PTB), and the chaperonin-like protein stimulator of TAR RNA-binding proteins (SRB). TRBP1 may act to disengage RNA polymerase II from TAR during transcriptional elongation if the RNA polymerase stalls at the TAR during transcriptional elongation.
UOM: 1 * 100 µG
Image Unavailable-PRSI91-452

Human recombinant ST6GAL1 (from cells)

Catalog Number: (PRSI91-452)
Supplier: ProSci Inc.
Description: The ST6GAL1 gene encodes beta -Galactosamide alpha-2,6-Sialyltransferase 1. It is a type II membrane protein and is localized to the trans-Golgi network. It catalyzes 2,6-sialylation of Gal beta 1,4-GlcNAc structures on N-glycans. ST6GAL1 is highly expressed in the liver and other tissues. ST6GAL1 deficiency causes abnormalities in B-cell immunoreactivity. The expression and activity of ST6GAL1 are associated with tumor metastasis in breast and colon cancers. The majority of ST6GAL1 in the liver is cleaved and secreted into the serum and may be used as a biomarker for hepatitis diseases.
UOM: 1 * 50 µG
Product Image-PRSI6097

Anti-ZIP9 Rabbit Polyclonal Antibody

Catalog Number: (PRSI6097)
Supplier: ProSci Inc.
Description: ZIP9 Antibody: The zinc transporter ZIP9, also known as SLC39A9, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP9 is a multipass membrane protein that belongs to the ZIP transporter subfamily I. It is located at the trans-Golgi network regardless of zinc presence and is thought to be a zinc homeostasis regulator acting in the secretory pathway without significantly altering cytosolic zinc homeostasis.
UOM: 1 * 100 µG
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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