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Catalog Number: (BOSSBS-3818R-A350)
Supplier: Bioss
Description: Growth differentiation factor 15 (GDF15) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. It has been implicated in a variety of functions directly related to tumorigenicity including antiproliferative and pro-apoptotic effects. BMP proteins are secreted growth factors that are characterized by seven conserved cysteine residues. In general, they are regulators of cell growth and differentiation in both embryonic and adult tissues.GDF15 is an important downstream mediator of DNA damage signaling and a transcriptional target of p53.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-6117R-CY3)
Supplier: Bioss
Description: May inhibit NODAL and BMP signaling during neural patterning (By similarity). May be a tumor suppressor in brain cancers.
UOM: 1 * 100 µl


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Supplier: VWR Collection
Description: Dissolved Oxygen Meter, VWR®

Catalog Number: (BOSSBS-3582R)
Supplier: Bioss
Description: Acts as an E3 ubiquitin-protein ligase. Promotes SMAD4 ubiquitination, nuclear exclusion and degradation via the ubiquitin proteasome pathway. According to PubMed:16751102, does not promote a decrease in the level of endogenous SMAD4. May act as a transcriptional repressor. Inhibits the transcriptional response to TGF-beta/BMP signaling cascade. Plays a role in the control of cell proliferation. Its association with SMAD2 and SMAD3 stimulates erythroid differentiation of hematopoietic stem/progenitor (By similarity). Monoubiquitinates SMAD4 and acts as an inhibitor of SMAD4-dependent TGF-beta/BMP signaling cascade (Monoubiquitination of SMAD4 hampers its ability to form a stable complex with activated SMAD2/3 resulting in inhibition of TGF-beta/BMP signaling cascade).
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-0699R-FITC)
Supplier: Bioss
Description: Probable acetyl-CoA transporter necessary for O-acetylation of gangliosides (PubMed:9096318). Negatively regulates BMP signaling (PubMed:25402622).
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-0699R-HRP)
Supplier: Bioss
Description: Probable acetyl-CoA transporter necessary for O-acetylation of gangliosides (PubMed:9096318). Negatively regulates BMP signaling (PubMed:25402622).
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-6117R-A680)
Supplier: Bioss
Description: May inhibit NODAL and BMP signaling during neural patterning (By similarity). May be a tumor suppressor in brain cancers.
UOM: 1 * 100 µl


Catalog Number: (MFLX72008-20)
Supplier: Avantor Fluid Handling
Description: DC-Powered motors are lightweight and portable – excellent for outdoor sampling and transfer of fluids.
UOM: 1 * 1 items


Catalog Number: (BOSSBS-1374R-HRP)
Supplier: Bioss
Description: BMPs (bone morphogenetic proteins) belong to the TGF beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF beta superfamily are disulfide-linked dimers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodelling and repair. Smad1 translocation to the nucleus is observed after the addition of BMP4 (also designated BMP2B), suggesting that BMP4 may play a role in activation of the Smad pathway. BMP is secreted into the extracellular matrix.
UOM: 1 * 100 µl


Catalog Number: (KIMB7432)
Supplier: KIMBERLY CLARK
Description: Kleenex® Wipes are ideal in busy healthcare environments. Available in a handy, portable POP-UP box, these wipes are soft, yet strong and can be used for multiple tasks.
UOM: 1 * 80 items


Supplier: Bertin Instruments
Description: Portable dry air sampler for bio contamination control.

Catalog Number: (BOSSBS-3860R-A555)
Supplier: Bioss
Description: CHRDL2 is a novel chordin like protein that can act as a BMP antagonist. Amember of the chordin family of proteins, it contains a signal peptide andthree CR (cysteine-rich repeat) domains. When expressed as a recombinantprotein it is secreted and binds to activin A, but not to BMP-2, -4, -6. Differential expression has been detected in developing chondrocytes, myoblasts, osteoblasts, and osteoarthritic joints. Complex alternative splicing of CHRDL2 potentially results in distinct isoforms that differ at their C termini, in the expression of signal peptide, and in the content of CR domains. CHRDL2 was originally characterized as a novel protein exclusively expressed in breast, lung, and colon tumors.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-3860R-A750)
Supplier: Bioss
Description: CHRDL2 is a novel chordin like protein that can act as a BMP antagonist. Amember of the chordin family of proteins, it contains a signal peptide andthree CR (cysteine-rich repeat) domains. When expressed as a recombinantprotein it is secreted and binds to activin A, but not to BMP-2, -4, -6. Differential expression has been detected in developing chondrocytes, myoblasts, osteoblasts, and osteoarthritic joints. Complex alternative splicing of CHRDL2 potentially results in distinct isoforms that differ at their C termini, in the expression of signal peptide, and in the content of CR domains. CHRDL2 was originally characterised as a novel protein exclusively expressed in breast, lung, and colon tumors.
UOM: 1 * 100 µl


Supplier: Avantor Fluid Handling
Description: Make the most of your Masterflex® pump with connection cables, replacement parts, and other accessories.

Catalog Number: (BRDY811217)
Supplier: Brady
Description: This portable storage station ensures that lockout devices remain easily accessible and ready for use whenever needed.
UOM: 1 * 1 items


Catalog Number: (611-3131)
Supplier: VWR Collection
Description: A complete portable system for density measurements, comprising of a portable balance plus a density kit for solids and liquids with the required accessories, all presented in a customised carrying case.
UOM: 1 * 1 KIT


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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