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Catalog Number: (ENZOBMLAK4040001)
Supplier: ENZO LIFE SCIENCES
Description: A QuantiZyme™ Assay System. The MMP-1 Colorimetric Drug Discovery Kit is a complete assay system designed to screen inhibitors of matrix metalloproteinase-1 (MMP-1, interstitial collagenase, fibroblast collagenase) using a thiopeptide as a chromogenic substrate.
UOM: 1 * 1 KIT


Supplier: ENZO LIFE SCIENCES
Description: Cell permeable non-tubulin-interacting mitosis inhibitor. Blocks mitosis (IC50=14µM) by binding to the mitotic kinesin Eg5.

Catalog Number: (ENZOALX430139M025)
Supplier: ENZO LIFE SCIENCES
Description: Topoisomerase I inhibitor
UOM: 1 * 25 mg


Supplier: ENZO LIFE SCIENCES
Description: Inhibitor of cAMP-dependent protein kinase (PKA), preferentially binding to type I PKA. Lipophilic analog of Rp-cAMPS. Resistant to mammalian cyclic nucleotide-dependent phosphodiesterases. Significantly more lipophilic and membrane permeant as compared to Rp-cAMPS or 8-Br-cAMP.

Catalog Number: (ENZOALX201178C100)
Supplier: ENZO LIFE SCIENCES
Description: Produced in <i>E. coli</i>.
UOM: 1 * 100 µG


Catalog Number: (ENZOENZABS4450100)
Supplier: ENZO LIFE SCIENCES
Description: Recommended Applications: ELISA, IP, WB

Species reactivity: Human, Mouse
UOM: 1 * 100 µG


Catalog Number: (ENZOADI905789100)
Supplier: ENZO LIFE SCIENCES
Description: Dopamine is the predominant catecholamine neurotransmitter in the mammalian brain, where it regulates locomotor, emotional, memory, and dietary intake functions, as well as peripheral roles such as hormone secretion and renal function. Dopamine receptors (D1-D5) are members of the seven transmembrane domain containing G-protein coupled receptor (GPCR) family A, and are the target of several anti-psychosis and anti-Parkinsonian drugs. The D2, D3, and D4 dopamine receptors are encoded by homologous intron-containing genes, and signal via coupling of Gi/Go alpha G-protein subunits to inhibit adenylyl cyclase activity, as well as modulate cellular ion channel conductance of K+ and Ca2+. This is in contrast to D1 and D5 dopamine receptors, which signal via Gs alpha subunits to activate adenylyl cyclase activity. Coactivation of D1 and D2 receptors has been shown to activate a Gq mediated pathway, stimulating phospholipase C (PLC) and mobilizing intracellular calcium stores. D1 receptors were initially characterized in the striatum and retina and are expressed throughout the brain in the olfactory tubercle, islands of Calleja, entopeduncular nucleus, neocortex, hippocampus, and amygdala. Expression of the D2 receptor is found primarily in the brain (striatum, olfactory tubercle, and nucleus accumbens) and in the anterior and intermediate lobes of the pituitary.
UOM: 1 * 100 µG


Supplier: ENZO LIFE SCIENCES
Description: Recommended Applications: IP, WB

Species reactivity:

Catalog Number: (ENZOBMLS1080005)
Supplier: ENZO LIFE SCIENCES
Description: A potent and selective inhibitor of α-L-fucosidases.
UOM: 1 * 5 mg


Catalog Number: (ENZOALX581014L002)
Supplier: ENZO LIFE SCIENCES
Description: TLR4 activator.
UOM: 1 * 2 mL


Supplier: ENZO LIFE SCIENCES
Description: DnaK possesses an autophosphorylation activity and a weak 5-nucleotidase activity, cleaving the 5 phosphate groups from both ribose and deoxyribose nucleotides. The role of DnaK in ATP-dependent protein-protein interactions has been extended to normal E. coli physiology, where, like eukaryotic Hsp70 homologs, it is thought to participate in the assembly/disassembly of protein complexes.

Catalog Number: (ENZOBMLNS1060025)
Supplier: ENZO LIFE SCIENCES
Description: Serotonin receptor ligand.
UOM: 1 * 25 mg


Supplier: ENZO LIFE SCIENCES
Description: Cell-permeable pyrrazolopyrimidine derivative that inhibits AMP kinase (Ki=109nM in the absence of AMP) in an ATP-competitive manner. It displays no significant inhibition of ZAPK, SYK, PKCT, PKA and JAK3. Decreases food intake in mice and inhibits the effects of AICAR and metformin. It has been shown to inhibit BMP type I receptors ALK2, ALK3 and ALK6. Promotes cardiomyogenesis in mouse embryonic stem cells. Induces protective autophagy in cancer cell lines.

Supplier: ENZO LIFE SCIENCES
Description: The assembly of individual mammalian proteasome subunits into catalytically active 20S proteasome is a complex process, with biogenesis of the mammalian 20S proteasome occuring via precursor complexes containing α and unprocessed β subunits. The pro-peptides of the β subunits are thought to prevent premature conversion of the precursor complexes into matured particles and are needed for efficient β subunit incorporation. The complex biogenesis is tightly regulated, requiring additional components such as the maturation factor POMP (proteasome maturation protein), an ubiquitous protein in eukaryotic cells. Mammalian POMP is functionally related to but not interchangable with its yeast homologue Ump1. POMP is associated purely with the precursor intermediates and is degraded upon final maturation. Northern blot experiments have revealed that expression of POMP is induced after treatment with interferon γ.

Supplier: ENZO LIFE SCIENCES
Description: DNA synthesis inhibitor

Catalog Number: (ENZOBMLP6060500)
Supplier: ENZO LIFE SCIENCES
Description: Negative control for Int-H1-S6A F8
UOM: 1 * 0,5 mg


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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