You Searched For: Chiral+Technologies

Supplier: BW TECHNOLOGIES

Description: Single gas detectors for safety and compliance in harsh environments with extreme temperatures.

Catalog Number: (736-0198)

Supplier: THERMO MATRIX TECHNOLOGIES

Description: PP. The square well geometry of this 96-well plate makes it ideal for bacterial growth applications.

UOM: 1 * 50 items

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Supplier: THERMO MATRIX TECHNOLOGIES

Description: Easy Peel, Microplate seal for ALPS 50V, Heat sealing film/foil/tape (96/384 wells), Single sheet/mat/strip, Film, heat sealing, Easy Peel film laminate

Supplier: THERMO MATRIX TECHNOLOGIES

Description: 96-well PP plates with square wells for storage and screening applications, as well as growth of bacterial cultures when used in conjuction with gas permeable adhesive seals.

Supplier: THERMO MATRIX TECHNOLOGIES

Description: These disposable automation reservoirs made of PP offer excellent chemical resistance. The reservoirs feature the same shape and dimensions as standard microplates, giving users the flexibility to handle reagents on virtually any automated liquid handler.

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Supplier: Primera Technology Europe

Description: Ribbons come in Standard, TC1 or TC2 quality.

Supplier: CHIRAL TECHNOLOGIES

Description: These columns are packed with Daicel’s coated polysaccharide-based chiral stationary phases (CSPs) which are manufactured by physically coating the polysaccharide derivatives onto silica matrices. Due to this manufacturing process, a choice of mobile phase components is typically narrower than with immobilised columns in order to minimise damage to the CSPs.

Supplier: THERMO MATRIX TECHNOLOGIES

Description: PP, translucent

Supplier: THERMO MATRIX TECHNOLOGIES

Description: PP or PS. These reservoirs offer an extra-wide base to add rigidity and stability, helping to avoid spills.

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Supplier: THERMO MATRIX TECHNOLOGIES

Description: PP. 96-well plates for sample storage.

Supplier: CHIRAL TECHNOLOGIES

Description: These columns allow chromatographers to employ essentially any organic solvent as mobile phase to develop methods for the most challenging separations. These columns are available in a variety of particle sizes and offer great speed and column resolving power. Columns packed with 3 µm CSPs offer high speed separations and a reduction in analysis time and cost per sample. Columns, packed with 3 µm particles, may be used in conventional HPLC units without significant loss in performance, even with the smaller column dimensions.

Catalog Number: (STMC02690)

Supplier: STEMCELL Technologies

Description: Serum-free culture supplement for expansion of human hematopoietic cells.

UOM: 1 * 1 mL

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Supplier: STEMCELL Technologies

Description: Interleukin 31 (IL-31), a four-helix bundle inflammatory cytokine, belongs to the IL-6 cytokine family which includes IL-6, oncostatin M, leukemia inhibitory factor (LIF), and cardiotrophin-1 ( Dillon <i>et al.</i>). IL-31 signals through a heterodimer composed of IL-31RA (also known as gp130-like receptor or GPL) and the oncostatin-M receptor (OSMR), both of which are expressed on monocytes (Diveu <i>et al.</i>; Ghilardi <i>et al.</i>), epithelial cells (Ip <i>et al.</i>), and keratinocytes (Kato <i>et al.</i>). Signaling through the GPL/OSMR complex activates the JAK/STAT, RAS/ERK, and PI3K/AKT signaling pathways, resulting in the downstream activation of STAT1, STAT3, and STAT5 transcription factors (Cornelissen <i>et al.</i>; Dambacher <i>et al.</i>; Dillon <i>et al.</i>; Ip <i>et al.</i>). IL-31 responses have been associated with allergic responses and inflammatory skin diseases including atopic dermatitis (Cornelissen <i>et al.</i>; Gangemi <i>et al.</i>).

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Supplier: STEMCELL Technologies

Description: Interleukin 19 (IL-19) is a member of the IL-10 cytokine family and is produced by keratinocytes, B cells, and monocytes (Romer <i>et al.</i>; Wolk <i>et al.</i>). Expression of IL-19 can be induced by granulocyte-macrophage colony-stimulating factor (GM-CSF) or lipopolysaccharide (LPS; Gallagher <i>et al.</i>). IL-19 is considered to be a proinflammatory cytokine, as it upregulates IL-6 and tumor necrosis factor alpha (TNF-α; Liao <i>et al.</i> 2002). IL-19 binds the IL-20 receptor complex (IL-20R) which comprises IL-20R alpha and IL-20R beta to activate the STAT3 pathway (Dumoutier <i>et al.</i>). IL-19 also induces T-helper cell differentiation towards a Th2 response, resulting in the production of IL-10 and additional IL-19 (Liao <i>et al.</i> 2002; Liao <i>et al.</i> 2004). IL-19 has been implicated in aging, vascular disease, Type I diabetes, and rheumatoid arthritis.

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Supplier: STEMCELL Technologies

Description: Transforming growth factor (TGF) beta 3 is a member of the TGF-β superfamily and regulates diverse cellular phenotypes. TGF-beta 3 binds to serine-threonine kinase type I and II receptors and activates signal transduction through SMAD2/3 proteins, thus regulating a variety of functions, including cell proliferation, differentiation, wound healing, apoptosis, and metabolism (Massagué; McDowell <i>et al.</i>). TGF-beta 3 enhances glycosaminoglycan production by mesenchymal stromal cells, stimulates scar-free healing, and improves glucose tolerance and phenotypic changes in adipocyte morphology (Hall <i>et al.</i>; Holton <i>et al.</i>). TGF-beta 3 induces proliferation of posterofrontal suture-derived mesenchymal stromal cells, and stimulates expression of fibroblast growth factors 2 and 18 (James <i>et al.</i>). This product is animal component-free.

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Supplier: STEMCELL Technologies

Description: Granulocyte-macrophage colony-stimulating factor (GM-CSF) promotes the proliferation and differentiation of hematopoietic progenitor cells and the generation of neutrophils, eosinophils, and macrophages. In synergy with other cytokines such as stem cell factor, IL-3, erythropoietin, and thrombopoietin, it also stimulates erythroid and megakaryocyte progenitor cells (Barreda <i>et al.</i>). GM-CSF is produced by multiple cell types, including stromal cells, Paneth cells, macrophages, dendritic cells (DCs), endothelial cells, smooth muscle cells, fibroblasts, chondrocytes, and Th1 and Th17 cells (Francisco-Cruz <i>et al.</i>). The receptor for GM-CSF (GM-CSFR) is composed of two subunits: the cytokine-specific α subunit (GMRα; CD116) and the common subunit βc (CD131) shared with IL-3 and IL-5 receptors (Broughton <i>et al.</i>). GM-CSFR is expressed on hematopoietic cells, including progenitor cells and immune cells, as well as non-hematopoietic cells. GM-CSF is able to stimulate the development of DCs that ingest, process, and present antigens to the immune system (Francisco-Cruz <i>et al.</i>).

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