You Searched For: Abcam

Description: G418 disulphate

Catalog Number: CAYM13200-1

UOM: 1 * 1 g

Supplier: Cayman Chemical

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Description: Fmoc-Osu (N-(9-fluorenylmethoxycarbonyloxy)succinimide)

Catalog Number: CAYM13861-25

UOM: 1 * 25 g

Supplier: Cayman Chemical

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Description: Anti-GABAA Rabbit Polyclonal Antibody

Catalog Number: CAYM10600-1

UOM: 1 * 1 items

Supplier: Cayman Chemical

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Description: Anti-GluR1 Rabbit Polyclonal Antibody

Catalog Number: CAYM10601-1

UOM: 1 * 1 items

Supplier: Cayman Chemical

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Description: 4-Pentynoyl-Coenzyme A (trifluoroacetate salt) ≥95%, lyophilised powder

Catalog Number: CAYM10547-500

UOM: 1 * 500 µG

Supplier: Cayman Chemical

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Description: Chenodeoxycholic acid

Catalog Number: CAYM10011286-10

UOM: 1 * 10 g

Supplier: Cayman Chemical

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Description: 8-Anilino-1-naphthalenesulphonic acid

Catalog Number: CAYM10010219-50

UOM: 1 * 50 g

Supplier: Cayman Chemical

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Description: A generic assay for the quantitation of therapeutic human IgG4 antibodies in monkey serum or plasma.

Catalog Number: CAYM500920-96

UOM: 1 * 1 items

Supplier: Cayman Chemical

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Description: For the measurement of anti-ovalbumin of the IgG1 isotype in mouse plasma and serum.

Catalog Number: CAYM500830-96

UOM: 1 * 1 items

Supplier: Cayman Chemical

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Description: A competitive assay for rapid screening for His-tagged proteins.

Catalog Number: CAYM10012445-96

UOM: 1 * 1 KIT

Supplier: Cayman Chemical

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Description: Hexadecanamide is a primary fatty acid amide that is derived from palmitic acid (C16:0) and belongs to a class of important cell signaling lipids.

Catalog Number: CAYM21086-250

UOM: 1 * 250 mg

Supplier: Cayman Chemical

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Description: Anti-STING mouse monoclonal antibody [clone: 8E7]

Catalog Number: CAYM25922-100

UOM: 1 * 100 µG

Supplier: Cayman Chemical

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Description: ML RR-S2 CDA is a synthetic cyclic dinucleotide (CDN) that contains non-canonical 2'5'-phosphodiester bonds and is an activator of stimulator of interferon genes (STING).1 It contains mixed linkages (ML) with both 2'5' and 3'5' linkages, which leads to increased thermal stability of human STING in a differential scanning fluorimetry (DSF) assay. ML RR-S2 CDA increases type I interferon production by THP-1 human monocytes relative to unmodified cyclic di-AMP (CDA; Item No. 17753), indicating the ML enhances its action at human STING. It induces expression of IFN-β and the pro-inflammatory cytokines TNF-α, IL-6, and Mcp-1 in murine bone marrow macrophages (BMM) isolated from wild-type, but not STING-/-, mice. ML RR-S2 CDA also induces IFN-β expression in peripheral blood mononuclear cells (PBMCs) isolated from donors carrying STINGWT/WT, STINGWT/REF, and STINGWT/HAQ alleles. In vivo, ML RR-S2 CDA initiates tumor regression and prevents tumor growth upon tumor cell reimplantation in 4T1 breast and CT26 colon cancer mouse xenograft models.

Catalog Number: CAYM24106-500

UOM: 1 * 500 µG

Supplier: Cayman Chemical

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Description: Meropenem ≥98%

Catalog Number: CAYM16068-100

UOM: 1 * 100 mg

Supplier: Cayman Chemical

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Description: β-D-Glucose ≥98%, crystalline solid

Catalog Number: CAYM16775-25

UOM: 1 * 25 g

Supplier: Cayman Chemical

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Description: WYE-125132 is an ATP-competitive inhibitor of mTOR (IC₅₀ = 0,19 nM) that inhibits signaling through both mTORC1 and mTORC2. It is selective for mTOR over phosphatidylinositol 3-kinase isoforms. WYE-125132 is effective against mTORC1 and mTORC2 in diverse cancer models, both <i>in vitro</i> and <i>in vivo</i>. Oral administration of WYE-125132 alone blocks mTOR signaling and prevents tumor growth in breast, lung, renal, and glioma cancer xenografts in mice, while combination therapy with the VEGF-inhibitor bevacizumab causes complete regression of A498 renal carcinoma tumors. In addition to its applications in cancer, WYE-125132 has been used to delineate novel aspects of mTOR signaling.

Catalog Number: CAYM18372-10

UOM: 1 * 10 mg

Supplier: Cayman Chemical

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