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Supplier: ENZO LIFE SCIENCES
Description: Circulating metabolite of PGE1 in man. Vasodilator equipotent with PGE12. Inhibits human platelet aggregation. Antimitotic activity.

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Supplier: ENZO LIFE SCIENCES
Description: Calpain inhibitor

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Catalog Number: (ENZOBMLPI1270100)
Supplier: ENZO LIFE SCIENCES
Description: Key inhibitor for use in proteasome research.
UOM: 1 * 100 µG

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Catalog Number: (ENZOBMLPI1230025)
Supplier: ENZO LIFE SCIENCES
Description: Tripeptidyl peptidase inhibitor
UOM: 1 * 25 mg

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Catalog Number: (ENZOALX400038M050)
Supplier: ENZO LIFE SCIENCES
Description: DNA alkylating agent.
UOM: 1 * 50 mg

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Catalog Number: (ENZOADIKAMCC210E)
Supplier: ENZO LIFE SCIENCES
Description: DNA-topoisomerase II, also known as Topo II or Top 2, is a multifunctional nuclear enzyme required during DNA replication, chromosome disjunction at mitosis, and other DNA-related activities because of its ability to alter DNA supercoiling. In mammalian cells, Topo II consists of two isozymes, Topo II-alpha (170kDa) and Topo II-beta (180kDa) and expression and localization of each isoform are distinct and stage specific during the cell cycle. Topo II-beta is expressed constitutively throughout the cell cycle, whereas the expression of Topo II-alpha is cell cycle-regulated, peaking in G2 to M phase and declining to a minimal level at the end of M phase. DNA-topoisomerase II is the target of some of the most active drugs used in chemotherapy and has been shown to have a critical role in neural development.
UOM: 1 * 100 µG

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Catalog Number: (ENZOADIKAPGP006E)
Supplier: ENZO LIFE SCIENCES
Description: The Rab family of GTP-binding proteins are members of the Ras superfamily of small G proteins, and participate in multiple steps of the membrane trafficking. Rab3A participates in the fusion of synaptic vesicles during neurotransmitter release, a process regulated by GDP/GDP exchange cofactors such as GAP, GDI, GRF, and rabphilin. Rab4 regulates recycling of proteins from the early endosome to the surface of many cell types, regulating glucose transporter and transferrin receptor cell surface localization. Rab5 regulates the fusion of plasma membrane-derived clathrin-coated vesicles with early endosomes and homotypic fusion among early endosomes.
UOM: 1 * 100 µG

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Catalog Number: (ENZOADIKAPST206E)
Supplier: ENZO LIFE SCIENCES
Description: IRAK (IL-1 associated serine/threonine kinase) is a critical regulator of IL-1 induced activation of the NF-κB pathway. IL-1 stimulates the association of IRAK with the heterodimer of IL-IRI and IL-IRAcP via the adapter protein MyD88. In addition to its role in IL-1 signaling, IRAK is a component of the signal transduction pathway through which TNF-R1 activates NF-κB dependent gene expression.
UOM: 1 * 100 µG

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Catalog Number: (ENZOADIKAPMA010E)
Supplier: ENZO LIFE SCIENCES
Description: MEK is a dual specificity kinase capable of phosphorylating both tyrosine and threonine residues. The MEK family, which is also known as MAP kinase kinase, phosphorylates MAP kinases on the conserved T-X-Y motif; phosphorylation of MAPK by MEK results in an increase in MAPK activity. MEK is involved in a diverse array of cellular processes such as stress-activated response, apoptosis, cytokine-induced cell proliferation, and DNA recombination during meiosis.
UOM: 1 * 100 µG

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Supplier: ENZO LIFE SCIENCES
Description: PARP5a inhibitor

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Catalog Number: (ENZOBMLWN1120005)
Supplier: ENZO LIFE SCIENCES
Description: Inhibits the recruitment of the co-activators β-catenin and GRIP1
UOM: 1 * 5 mg

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Catalog Number: (ENZOBMLUW05600100)
Supplier: ENZO LIFE SCIENCES
Description: Produced in <i>E. coli</i>.
UOM: 1 * 100 µG

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Catalog Number: (ENZOBMLUW02000025)
Supplier: ENZO LIFE SCIENCES
Description: Produced in <i>E. coli</i>.
UOM: 1 * 25 µG

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Catalog Number: (ENZOBMLUW06800100)
Supplier: ENZO LIFE SCIENCES
Description: Produced in<i> E. coli</i>.
UOM: 1 * 100 µG

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Catalog Number: (ENZOALX480066M005)
Supplier: ENZO LIFE SCIENCES
Description: ATP analog that can substitute ATP in various kinase reactions. Substrate and inhibitor of ATP-dependent enzyme systems. The resulting thiophosphorylated proteins are resistant to dephosphorylation by protein phosphatases. Increases the activity of Ca2 -activated K channels.
UOM: 1 * 5 mg

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Catalog Number: (ENZOALX500009G005)
Supplier: ENZO LIFE SCIENCES
Description: Octyl-β-D-thioglucopyranoside
UOM: 1 * 5 g

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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