You Searched For: MP Biomedicals

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2,6-Di-tert-butyl-p-cresol, crystalline powder

Supplier: MP Biomedicals

Description: Butylated hydroxytoluene is a phenolic antioxidant.

Polymyxin B sulphate

Supplier: MP Biomedicals

Description: Polymyxin B sulphate is a mixture of Polymyxin B1 and Polymyxin B2 sulphate, obtained from Bacillus polymyxia strains. Polymyxin B inhibits gram-negative organisms<i> in vitro</i> wherein it binds to and interferes with the permeability of the bacterial cytoplasmic membrane and is also reported to inhibit Ca<sup>2+</sup> dependent protein kinase C (PKC). Effective concentration is typically 50 mg/l.

L-Methionine

Supplier: MP Biomedicals

Description: L-Methionine

Agarose, white powder, high resolution for molecular biology

Catalog Number: (ICNA11AGAR0050)

Supplier: MP Biomedicals

Description: Agarose High Resolution is an intermediate melting agarose with approximately twice the resolution capability of routine agarose. It is a purified linear galactan hydrocolloid isolated from agar or agar-bearing marine algae. It is ideal for the resolution of small DNA fragments in the range 20 bp to 2000 bp.
Agarose high resolution is an intermediate melting and gelling point agarose which exhibits superior sieving characteristics. It is recommended for analytical gels of DNA fragments under 1000 bp and is ideal for small DNA fragments down to 20 bp can be separated on 6 % gels. It resolves fragments differing in size by only 2 bp. Its use avoids the need for PAGE Southern and Northern transfers can be achieved efficiently from them at concentrations up to 2%. DNA fragments can be purified with high efficiency from this agarose gels up to 4% by using either a purification kit or an electroelution system.

UOM: 1 * 50 g

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Silicon dioxide, Silitech

Catalog Number: (ICNA0202071)

Supplier: MP Biomedicals

Description: Mean Pore Size: 60Å
Particle Size: 32-63 µm

UOM: 1 * 25 kg

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Tamoxifen, white powder

Supplier: MP Biomedicals

Description: Protein kinase C inhibitor (IC50 = 50-200 µM depending on assay conditions in MCF-7 cells or IC50 = 100 µM in rat brain). The PKC inhibition is also dependent on the phosopholipid concentration. Also inhibits both calmodulin-dependent and calmodulin-independent Ca2+-, Mg2+-ATPase. Tamoxifen is a selective estrogen response modifier (SERM), anti-angiogenetic factor. It is a prodrug that is metabolized to active metabolites 4-hydroxytamoxifen (4-OHT) and endoxifen by cytochrome P450 isoforms CYP2D6 and CYP3A4. In breast cancer, the gene repressor activity of tamoxifen against ERBB2 is dependent upon PAX2. Blocks estradiol-stimulated VEGF production in breast tumor cells.
Tamoxifen has been used to facilitate the recombination of ect2flox allele in mouse organs. It has also been used to study its effect on lipopolysaccharide (LPS)-induced microglial activation
Tamoxifen is a Protein kinase C inhibitor. It induces apoptosis in human malignant glioma cell lines. Tamoxifen and its metabolite 4-hydroxytamoxifen are selective estrogen response modifiers (SERMs) that act as estrogen antagonists in mammary gland. Blocks estradiol-stimulated VEGF production in breast tumor cells.

Flavobacterium meningosepticum Proline specific endopeptidase, MP Biomedicals

Catalog Number: (ICNA08320821)

Supplier: MP Biomedicals

Description: Proline specific endopeptidase specifically cleaves peptide bonds on the carboxy side of proline residues.

UOM: 1 * 50 AU

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Polyethyleneimine, M.W. 50,000 - 100,000 50% in aqueous solution, viscous solution

Supplier: MP Biomedicals

Description: Polyethylenimine is a branched chain polymer having a ratio of 1:2:1 of primary:secondary:tertiary amines with a branching site every 3 to 3,5 nitrogen atoms and a base structure of (CH₂CH₂NH)x. The nitrogen atoms must be protonated to achieve cationic charge, so the cationic charge density is pH dependent.

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