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Catalog Number: (PRSI31-369)
Supplier: ProSci Inc.
Description: The function remains unknown.
UOM: 1 * 100 µG


Catalog Number: (PRSI36-330)
Supplier: ProSci Inc.
Description: SLP-2 (stomatin-like protein 2) is an unusual stomatin homolog. IT is a mitochondrial protein and functions in energy process by MMP maintenance, and subsequently affecting cell motility, proliferation and chemosensitivity. SLP-2 was identified as a cancer-related gene overexpressed in human ESCC, lung cancer, laryngeal cancer, and endometrial adenocarcinoma. In tumor cells, SLP-2 promotes cell growth, cell adhesion, and tumorigenesis.
UOM: 1 * 100 µG


Catalog Number: (PRSI92-263)
Supplier: ProSci Inc.
Description: Dipeptidyl peptidase 3(DPP3), is a member of the S9B family in clan SC of the serine proteases. DPP3 has post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. This cytoplasmic protein binds a single zinc ion with its zinc-binding motif (HELLGH). It releases an N-terminal dipeptide from a peptide comprising four or more residues, with broad specificity and also acts on dipeptidyl 2-naphthylamides.Increased activity of this protein has a relationship with endometrial and ovarian cancers.
UOM: 1 * 50 µG


Catalog Number: (PRSI96-106)
Supplier: ProSci Inc.
Description: T-cell surface glycoprotein CD4 is also known as T-cell surface antigen T4/Leu-3. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is accessory protein for MHC class-II antigen/T-cell receptor interaction. CD4 induces the aggregation of lipid rafts. CD4 is a primary receptor used by HIV-1 to gain entry into host T cells. HIV infection leads to a progressive reduction of the number of T cells possessing CD4 receptors. Therefore, medical professionals refer to the CD4 count to decide when to begin treatment for HIV-infected patients.
UOM: 1 * 100 µG


Catalog Number: (PRSI92-253)
Supplier: ProSci Inc.
Description: Eukaryotic translation initiation factor 4E is a 217 amino acids protein that belongs to the eukaryotic initiation factor 4E family. eIF4F is a multi-subunit complex, the composition of which varies with external and internal environmental conditions. It is composed of at least EIF4A, EIF4E and EIF4G1/EIF4G3. EIF4E is also known to interact with other partners.It can recognize and bind the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.
UOM: 1 * 50 µG


Catalog Number: (PRSI70-395)
Supplier: ProSci Inc.
Description: Anti-TCF7L2 Rabbit Polyclonal Antibody
UOM: 1 * 50 µl


Catalog Number: (PRSI51-765)
Supplier: ProSci Inc.
Description: Anti-MEOX2 Mouse Monoclonal Antibody
UOM: 1 * 50 µG


Catalog Number: (PRSI79-302)
Supplier: ProSci Inc.
Description: The protein encoded by BAD gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.
UOM: 1 * 100 µG


Catalog Number: (PRSI79-309)
Supplier: ProSci Inc.
Description: Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Not activated by EGF, TGF-alpha and amphiregulin.
UOM: 1 * 100 µG


Catalog Number: (PRSI79-326)
Supplier: ProSci Inc.
Description: Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor.
UOM: 1 * 100 µG


Catalog Number: (PRSI79-328)
Supplier: ProSci Inc.
Description: Acts as part of the IKK complex in the conventional pathway of NF-κ-B activation and phosphorylates inhibitors of NF-κ-B thus leading to the dissociation of the inhibitor/NF-κ-B complex and ultimately the degradation of the inhibitor. As part of the non-canonical pathway of NF-κ-B activation, the MAP3K14-activated CHUK/IKKA homodimer phosphorylates NFKB2/p100 associated with RelB, inducing its proteolytic processing to NFKB2/p52 and the formation of NF-κ-B RelB-p52 complexes. Also phosphorylates NCOA3. Phosphorylates 'Ser-10' of histone H3 at NF-κ-B-regulated promoters during inflammatory responses triggered by cytokines.
UOM: 1 * 100 µG


Catalog Number: (PRSI71-063)
Supplier: ProSci Inc.
Description: Anti-CASR Rabbit Polyclonal Antibody
UOM: 1 * 250 µl


Catalog Number: (PRSI51-816)
Supplier: ProSci Inc.
Description: Anti-TSG101 Mouse Monoclonal Antibody
UOM: 1 * 50 µG


Catalog Number: (PRSI79-364)
Supplier: ProSci Inc.
Description: Involved in the regulation of cell adhesion and in signal transduction through the Wnt pathway.
UOM: 1 * 100 µG


Catalog Number: (PRSI79-370)
Supplier: ProSci Inc.
Description: Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear
UOM: 1 * 100 µG


Catalog Number: (PRSI79-353)
Supplier: ProSci Inc.
Description: This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. Essential for T-cell receptor (TCR)-mediated T-cell activation, but is dispensable during TCR-dependent thymocyte development. Links the TCR signaling complex to the activation of NF-κ-B in mature T lymphocytes. Required for interleukin-2 (IL2) production. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters.
UOM: 1 * 100 µG


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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