You Searched For: SELENOZYME

Supplier: SELENOZYME

Description: The human DIO3 selenoprotein is encoded by the DIO3 gene and catalyzes the inactivation of thyroid hormone by inner ring deiodination of the prohormone thyroxine (T4) and the bioactive hormone 3,3',5-triiodothyronine (T3) to inactive metabolites, 3,3',5'- triiodothyronine (RT3) and 3,3'-diiodothyronine (T2), respectively.
We provide the human DIO3 enzyme with approx. 20% Sec contents, mixed with inactive forms containing Sec-to-Lys and Sec-to-Gln substitutions, at more than 95% purity in aliquots at amounts from 50 to 500 µg.

Supplier: SELENOZYME

Description: The human TrxR1 selenoprotein is encoded by the TXNRD1 gene and exerts a wide range of functions in cytosolic redox control and antioxidant systems. We provide the main cytosolic isoform of the human TrxR1 enzyme with more than 90% Sec contents and more than 95% purity in aliquots at amounts from 5 to 50 units.

Supplier: SELENOZYME

Description: The human TrxR2 selenoprotein is encoded by the TXNRD2 gene and exerts a wide range of functions in mitochondrial redox control and antioxidant systems. We provide the main mitochondrial isoform of the human TrxR2 enzyme with more than 90% Sec contents and more than 95% purity in aliquots at amounts from 5 to 50 units.

Supplier: SELENOZYME

Description: The human GPX1 selenoprotein is encoded by the GPX1 gene and has potent hydrogen peroxide reducing activity using glutathione.
We provide the human GPX1 enzyme with approx. 20% Sec contents, mixed with inactive forms containing Sec-to-Lys and Sec-to-Gln substitutions, at more than 95% purity in aliquots at amounts from 0,5 to 5 units.

Supplier: SELENOZYME

Description: The human GPX2 selenoprotein is encoded by the GPX2 gene and has potent hydrogen peroxide reducing activity using glutathione.
We provide the human GPX2 enzyme with approx. 20% Sec contents, mixed with inactive forms containing Sec-to-Lys and Sec-to-Gln substitutions, at more than 95% purity in aliquots at amounts from 0,5 to 5 units.

Supplier: SELENOZYME

Description: The human GPX4 selenoprotein is encoded by the GPX4 gene and has hydrogen peroxide and lipid hydroperoxide reducing activity using glutathione, protecting cells from ferroptosis.
We provide a high specific activity human GPX4 which is purified to yield close to 100% selenocysteine content. This product is offered at amounts ranging from 2,5 to 25 units.

Supplier: SELENOZYME

Description: The human DIO2 selenocprotein is encoded by the DIO2 gene and catalyzes the conversion of prohormone thyroxine (3,5,3',5'-tetraiodothyronine, T4) to the bioactive thyroid hormone (3,5,3'-triiodothyronine, T3) by outer ring 5'-deiodination.
We provide the human DIO2 enzyme with approx. 20% Sec contents, mixed with inactive forms containing Sec-to-Lys and Sec-to-Gln substitutions, at more than 95% purity in aliquots at amounts from 50 to 500 µg.

Supplier: SELENOZYME

Description: The TGR selenoprotein of Schistosoma mansoni is the only major reductive cytosolic flavoprotein of this parasite, taking over the combined role of TrxR1 and glutathione reductase, thereby exerting a wide range of functions in redox control and antioxidant systems and being a promising drug target for treatment of schistosomiasis.
We provide the main the Schistosoma mansoni TGR enzyme with more than 90% Sec contents and more than 95% purity in aliquots at amounts from 5 to 50 units.

Supplier: SELENOZYME

Description: The TrxR enzyme in C. elegans is the single selenoprotein in this organism, exerting a wide range of functions in redox control and for antioxidant systems. It is also together with glutathione reductase essential for the molting process.
We provide the main isoform of the C. elegans TrxR enzyme with more than 90% Sec contents and more than 95% purity in aliquots at amounts from 5 to 50 units.

Supplier: SELENOZYME

Description: The rat TrxR1 selenoprotein is encoded by the rat Txnrd1 gene and exerts a wide range of functions in cytosolic redox control and antioxidant systems.
We provide the main cytosolic isoform of the rat TrxR1 enzyme with more than 90% Sec contents and more than 95% purity in aliquots at amounts from 5 to 50 units.

Supplier: SELENOZYME

Description: The rat TrxR2 selenoprotein is encoded by the rat Txnrd2 gene and exerts a wide range of functions in cytosolic redox control and antioxidant systems.
We provide the main cytosolic isoform of the rat TrxR2 enzyme with more than 90% Sec contents and more than 95% purity in aliquots at amounts from 5 to 50 units.

Supplier: SELENOZYME

Description: The human GPX4 selenoprotein is encoded by the GPX4 gene and has hydrogen peroxide and lipid hydroperoxide reducing activity using glutathione, protecting cells from ferroptosis.
We provide the human GPX4 enzyme with approx. 20% Sec contents, mixed with inactive forms containing Sec-to-Lys and Sec-to-Gln substitutions, at more than 95% purity in aliquots at amounts from 0,5 to 5 units.