Anti-CHK1 Mouse Monoclonal Antibody

Supplier: ENZO LIFE SCIENCES
ADI905770100
ENZOADI905770100EA 371 EUR
ENZOADI905770100
Anti-CHK1 Mouse Monoclonal Antibody
Antibodies
The DNA damage checkpoint is a signal transduction pathway that has the ability to delay entry into mitosis. When DNA is damaged, the Check point kinases (CHKs) are known to act downstream of ATM to elicit appropriate responses such as cell cycle arrest. Chk1, for instance, is activated by ATM phosphorylation of serines 123, 178, 278, and 292 of the S phase-promoting cdc25A phosphatase and accelerates IR (ionizing radiation)induced degradation of cdc25A.

  • For Western Blot

Recognizes human, mouse and rat Chk1. Detects a band of ~55kDa by Western blot.

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