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Product Image-ICNA0219989650

AlbumiNZ™ Bovine serum albumin (BSA), MP Biomedicals

Supplier: MP Biomedicals
Description: AlbumiNZ™ Bovine albumin is a single polypeptide chain consisting of approximately 583 to 595 amino acid residues and no carbohydrates. At pH 5 to 7 it contains 17 intrachain disulphide bridges and 1 sulphydryl group.

Product Image-PIER77701

Immobilised reductant column

Catalog Number: (PIER77701)
Supplier: Thermo Fisher Scientific
Description: Pierce™ Immobilised reductant column contains beaded resin to which an thiol-based reducing agent has been immobilised to enable solid-phase reduction of peptide and protein disulphide bonds.
UOM: 1 * 2 mL
Image Unavailable-ENZOADISPA891PEF

Anti-PDI Mouse Monoclonal Antibody (PE (Phycoerythrin))

Supplier: ENZO LIFE SCIENCES
Description: The mammalian protein disulphide-isomerase (PDI) family encompasses several highly divergent proteins involved in the processing and maturation of secretory proteins in the ER by catalyzing the rearrangement of disulphide bonds. PDI, an abundant protein of the ER (>400uM), contains a carboxy-terminal retention signal sequence, KDEL, similar to that of BiP and Grp94. The PDI proteins are characterized by the presence of one or more domains of ~95-110 amino acids related to the cytoplasmic protein thioredoxin. All but the PDI-D subfamily are composed entirely of repeats of such domains, with at least one domain containing - and one domain lacking - a redox-active-Cys-X-X-Cys-tetrapeptide. In addition to roles as redox catalysts and isomerases, PDI proteins perform such functions as peptide binding and cell adhesion, and may conduct chaperone activities. Platelet surface thiols and disulphides play an important role in platelet responses. Catalytically active PDI resides on platelet surfaces where it mediates platelet aggregation and secretion by reducing disulfide bonds, thus exposing fibrinogen receptors in platelets.

Image Unavailable-PRSI33-280

Anti-CD8A Mouse Monoclonal Antibody [clone: RIV11]

Catalog Number: (PRSI33-280)
Supplier: ProSci Inc.
Description: CD8 molecule consists of two chains, termed alpha and beta chain, which are expressed as a disulphide-linked heterodimer or homodimer. CD8 is expressed on T cell subset (cytotoxic/suppressor T cells), thymocytes and NK cells.
UOM: 1 * 100 µG
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Anti-CD8A Mouse Monoclonal Antibody [clone: SPM548]

Catalog Number: (PRSI33-281)
Supplier: ProSci Inc.
Description: CD8 molecule consists of two chains, termed alpha and beta chain, which are expressed as a disulphide-linked heterodimer or homodimer. CD8 is expressed on T cell subset (cytotoxic/suppressor T cells), thymocytes and NK cells.
UOM: 1 * 100 µG
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L(-)-Glutathione (reduced form) ≥98%, off-white powder

Supplier: MP Biomedicals
Description: Glutathione suppresses human immunodeficiency virus expression in chronically infected monocytic cells. It is a useful tripeptide involved in many aspects of metabolism, including transport of g-glutamyl amino acids and reductive cleavage of disulphide bonds.

Product Image-PIER77720

TCEP solution, neutral pH, Bond-Breaker™ Pierce™

Catalog Number: (PIER77720)
Supplier: Thermo Fisher Scientific
Description: Bond-Breaker™ TCEP Solution (neutral pH) is a stable, 0,5 M solution of the thiol-free, phosphine-based TCEP compound, useful as a 10X stock for addition to SDS-PAGE sample loading buffers to reduce protein disulphide bonds.
UOM: 1 * 5 mL

MSDS Certificates


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N-Acetyl-L-cysteine ≥96%, white crystalline powder

Supplier: MP Biomedicals
Description: N-Acetyl-L-cysteine is an acetylated amino acid with antioxidant and mucolytic properties, as a mucolytic, N-Acetyl-L-cysteine serves to dissipate disulphide bonds across mucoproteins, loosening and clearing the viscosity of sputum. It increases cellular pools of free radical scavengers.

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1,1'-Azobis(N,N-dimethylformamide), yellow crystals

Supplier: MP Biomedicals
Description: Diamide is used as a thiol oxidising agent. It has also been used to titrate protein glutathiolation to discriminate from other oxidative protein modifications. Diamide treatment increased protein glutathiolation in a concentration-dependent manner and had comparably little effect on protein-protein disulphide formation.

Image Unavailable-BOSSBS-4687R-HRP

Anti-AMH Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-4687R-HRP)
Supplier: Bioss
Description: Anti mullerian hormone (AMH) is a member of the TGF beta superfamily. It is secreted as a homodimeric 140kD disulphide linked precursor that is cleaved to release the mature 30kD homodimer. Originally classified as a foetal testicular hormone that inhibits Mullerian duct development, AMH is expressed post natally by immature Sertoli cells, and to a lesser degree by granulosa cells. AMH plays a role in testicular differentiation and in the regulation of ovarian follicle growth.
UOM: 1 * 100 µl
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Bovine aprotinin (from Lung), MP Biomedicals

Supplier: MP Biomedicals
Description: Aprotinin is a protein consisting of 58 amino acids, arranged in a single polypeptide chain that is cross-linked by three disulphide bridges. It is found in bovine lymph nodes, lung, parotid gland, spleen, liver, pancreas, seminal vesicles, thyroid gland, kidney, mucous membranes of the trachea and esophagus, ovaries, heart, posterior pituitary and cartilage.

Image Unavailable-ICNA0219038210

Bovine aprotinin (from Lung), MP Biomedicals

Supplier: MP Biomedicals
Description: Aprotinin is a protein consisting of 58 amino acids, arranged in a single polypeptide chain that is cross-linked by three disulphide bridges. It is found in bovine lymph nodes, lung, parotid gland, spleen, liver, pancreas, seminal vesicles, thyroid gland, kidney, mucous membranes of the trachea and esophagus, ovaries, heart, posterior pituitary and cartilage.

Image Unavailable-PRSI91-071

Human recombinant Cystatin A (from E. coli)

Catalog Number: (PRSI91-071)
Supplier: ProSci Inc.
Description: Human Cystatin A (CSTA) is a member of family 1 of the cystatin superfamily, which is characterized by lacking of disulphide bonds an carbohydrates. Cystatin A is an intracellular inhibitor regulating the activities of cysteine proteases of the papain family such as Cathepsins B, H and L. Cystatin A is also implicated in a number of disease states. Due to altered proteolytic state in cancer progression, Cystatin A may play a role in the proteolytic pathways.
UOM: 1 * 50 µG
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Anti-SLC3A2 Mouse Monoclonal Antibody (CF647) [clone: UM7F8]

Supplier: Biotium
Description: CD98 exits as a heterodimer containing a disulphide-linked glycosylated heavy chain and a non-glycosylated light chain. It is a member of the solute carrier family and encodes a cell surface, transmembrane protein. The protein exists as the heavy chain of a heterodimer, covalently bound through disulfide bonds to one of several possible light chains. The encoded transporter plays a role in regulation of intracellular calcium levels and transports L-type amino acids. Alternatively spliced transcript variants, encoding different isoforms, have been characterized.

Image Unavailable-BNC400425-100

Anti-SLC3A2 Mouse Monoclonal Antibody (CF640R) [clone: UM7F8]

Supplier: Biotium
Description: CD98 exits as a heterodimer containing a disulphide-linked glycosylated heavy chain and a non-glycosylated light chain. It is a member of the solute carrier family and encodes a cell surface, transmembrane protein. The protein exists as the heavy chain of a heterodimer, covalently bound through disulfide bonds to one of several possible light chains. The encoded transporter plays a role in regulation of intracellular calcium levels and transports L-type amino acids. Alternatively spliced transcript variants, encoding different isoforms, have been characterized.

Image Unavailable-BNC940425-100

Anti-SLC3A2 Mouse Monoclonal Antibody (CF594) [clone: UM7F8]

Supplier: Biotium
Description: CD98 exits as a heterodimer containing a disulphide-linked glycosylated heavy chain and a non-glycosylated light chain. It is a member of the solute carrier family and encodes a cell surface, transmembrane protein. The protein exists as the heavy chain of a heterodimer, covalently bound through disulfide bonds to one of several possible light chains. The encoded transporter plays a role in regulation of intracellular calcium levels and transports L-type amino acids. Alternatively spliced transcript variants, encoding different isoforms, have been characterized.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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