Resveratrol ≥98% (by TLC)
Supplier: ENZO LIFE SCIENCES AG
Synonyms:
trans-3,4,5-Trihydroxystilbene, (E)-5-(4-Hydroxystyryl)benzene-1,3-diol
Antioxidant. SIRT1 activator.
Phenolic antioxidant found in grapes and wine. Potent activator of human deacetylase SIRT1 (maximum effect at 100-200μM). Increases longevity in yeast. Displays antiproliferative effect on human breast epithelial cells. Displays a variety of pharmacological activities including: estrogen receptor agonist activity, inhibition of ribonucleotide reductase and DNA synthesis, inhibition of eicosanoid synthesis, cell cycle arrest at S/G2 phase and induction of apoptosis. Inhibits PKD in vitro (IC50=200μM) and in vivo (IC50=800μM), but not PKC isoforms. Protects against 4-hydroxynonenal (4-HNE) induced oxidative stress and apoptosis. Shows cancer chemopreventive activity. Specific inhibitor of cyclooxygenase-1 (COX-1). Inhibits the hydroperoxidase activity of COX-1.
Formula:
C₁₄H₁₂O₃ MW: 228,25 g/mol |
MDL Number:
MFCD00133799 CAS Number: 501-36-0 |
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