Phorbol-12-myristate-13-acetate ≥99% (by HPLC, TLC)
Supplier: ENZO LIFE SCIENCES
Synonyms:
TPA, Phorbol 12-myristate 13-acetate, 12-O-Tetradecanoylphorbol 13-acetate, 4β,9α,12β,13α,20-Pentahydroxytiglia-1,6-dien-3-one 12-tetradecanoate 13-acetate, (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9a-Acetoxy-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-1H-cyclopropa[3,4]benzo[1,2-e]azulen-9-yl tetradecanoate
PKC activator (10 to 100 ng/ml).
- Most commonly used phorbol ester
- Causes an extremely wide range of effects in cells and tissues
- Colorless amorphous film or foam.
- Soluble in DMSO (25 mg/ml); 100% ethanol (25 mg/ml); acetone, ether or dimethyl formamide
Very potent mouse skin tumor promoter. Inhibits apoptosis induced by Fas, but induces apoptosis in HL-60 promyelocytic leukemia cells.
Formula:
C₃₆H₅₆O₈ MW: 616.836 g/mol Storage Temperature: Freezer |
MDL Number:
MFCD00036736 CAS Number: 16561-29-8 |
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