C75 ≥98%

Supplier: ENZO LIFE SCIENCES

Synonyms: trans-4-Methylene-2-octyl-5-oxotetrahydrofuran-3-carboxylic acid

ALX270286M001 ALX270286M005
ENZOALX270286M001EA 124 EUR
ENZOALX270286M001 ENZOALX270286M005
C75 ≥98%
C75

Fatty acid synthase inhibitor


Inhibitor of fatty acid synthase (FAS) reducing food intake and body weight in mice. Exhibits irreversible slow-binding biphasic inactivation of fatty acid synthase. Downregulates neuropeptide Y and Agouti-related protein expression. Has been proposed to activate CPT-1 activity in liver and adipose tissue, leading to increased fatty acid oxidation and energy production. Shows significant in vivo antitumor activity in human breast cancer cells. Suppresses DNA replication and induces apoptosis. FAS inhibition by C75 leads to a dramatic accumulation of the CDK inhibitor p27KIP1 from cytosol to cell nuclei.


Synthetic.

Formula: C₁₄H₂₂O₄
MW: 254.3221 g/mol
MDL Number: MFCD03265452
CAS Number: 191282-48-1

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