Compound E ≥98% (by HPLC)
Supplier: ENZO LIFE SCIENCES AG
Synonyms:
(S)-2-(2-(3,5-Difluorophenyl)acetamido)-N-((S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)propanamide
ALX270415C250
ALX270415M001
ENZOALX270415C250EA
198
EUR
ENZOALX270415C250
ENZOALX270415M001
Compound E ≥98% (by HPLC)
Compound E
gamma-Secretase inhibitor
Cell permeable, potent, selective, non-transition state and non-competitive inhibitor of γ-secretase (IC50=0.3nM for total β-amyloid) and Notch processing. At higher concentrations (20-400µM), only weakly affects the presenilase activity. Activity tested!
Formula:
C₂₇H₂₄F₂N₄O₃ MW: 490,511 g/mol |
MDL Number:
MFCD04974531 CAS Number: 209986-17-4 |
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