AS601245 sum of isomers ≥95% (by HPLC)

Supplier: ENZO LIFE SCIENCES

Synonyms: (Z)-2-(benzo[d]thiazol-2-yl)-2-(2-((2-(pyridin-3-yl)ethyl)imino)-1,2-dihydropyrimidin-4-yl)acetonitrile, (2Z)-2-(3H-1,3-Benzothiazol-2-ylidene)-2-[2-(2-pyridin-3-ylethylamino)pyrimidin-4-yl]acetonitrile, SAPK Inhibitor V, 2-(Benzo[d]thiazol-2-yl)-2-(2-((2-(pyridin-3-yl)ethyl)amino)pyrimidin-4-yl)acetonitrile, 1,3-Benzothiazol-2-yl-(2-((2-(3-pyridinyl)ethyl)amino)-4-pyrimidinyl)acetonitrile

ALX270443M001 ALX270443M005 ALX270443M025
ENZOALX270443M001EA 90.2 EUR
ENZOALX270443M001 ENZOALX270443M005 ENZOALX270443M025
AS601245 sum of isomers ≥95% (by HPLC)
AS601245

Jnk inhibitor


Potent and cell permeable ATP competitive JNK inhibitor (hJNK1: IC50=150nM, hJNK2: IC50=220nM and hJNK3: IC50=70 nM). Displays anti-inflammatory properties and has been shown to reduce TNF-α plasma levels induced by LPS in mice.

Formula: C₂₀H₁₆N₆S
MW: 372,45 g/mol
MDL Number: MFCD07772196
CAS Number: 345987-15-7

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