RO-3306 ≥95% (by 1H-NMR)
Supplier: ENZO LIFE SCIENCES AG
Synonyms:
(Z)-5-(Quinolin-6-ylmethylene)-2-((thiophen-2-ylmethyl)amino)thiazol-4(5H)-one, (Z)-5-(Quinolin-6-ylmethylene)-2-[(thiophen-2-ylmethyl)amino]thiazol-4(5H)-one
ALX270463M001
ALX270463M005
ENZOALX270463M001EA
81.4
EUR
ENZOALX270463M001
ENZOALX270463M005
RO-3306 ≥95% (by 1H-NMR)
RO-3306
CDK/cyclin inhibitor
Inhibitor of CDK1/cyclin B1 and CDK1/cyclin A. Reversibly arrests human cells at the G2/M border of the cell cycle. Allows for effective cell synchronisation in early mitosis. Downregulates expression of the antiapoptotic proteins Bcl-2 and survivin and blocks p53-mediated induction of p21 and MDM2.
Formula:
C₁₈H₁₃N₃OS₂ MW: 351,5 g/mol |
MDL Number:
MFCD17392573 CAS Number: 872573-93-8 |
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