[-]-Deguelin ≥95% (by HPLC)
Supplier: ENZO LIFE SCIENCES
ALX350118M005
ALX350118M025
ENZOALX350118M005EA
124
EUR
ENZOALX350118M005
ENZOALX350118M025
[-]-Deguelin ≥95% (by HPLC)
[-]-Deguelin
COX-2 inhibitor
Inhibitor of Akt (protein kinase B; PKB) in an in vitro lung carcinogenesis progression model. Inhibits cell proliferation - cells accumulate in the G2-M phase of the cell cycle. Premalignant and malignant human brochial epithelial cells are highly sensitive to deguelin compared to normal cells. Induces apoptosis. Exhibits a marked inhibitory effect on mouse skin tumor promotion in an in vivo two-stage carcinogenesis test. Inhibits cyclooxygenase-2 (COX-2) expression.
Formula:
C₂₃H₂₂O₆ Storage Temperature: Refrigerator |
MDL Number:
MFCD01740600 CAS Number: 522-17-8 |
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