Compound A ≥98% (by HPLC)
Supplier: Enzo Life Sciences
Glucocorticoid receptor modulator.
Cell permeable, nonsteroidal glucocorticoid receptor modulator with high binding affinity.
Exerts anti-inflammatory potential by down-modulating TNF-induced pro-inflammatory gene expression, such as IL-6 and E-selectin. Unlike dexamethasone it does not enhance glucocorticoid response element (GRE)-driven gene expression or induce glucocorticoid receptor (GR) binding to GRE-dependent genes in vivo.
Soluble in DMSO, 100% ethanol or water.
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