α-Hydroxy-o-tolyl-β-D-glucopyranoside, powder
Supplier: MP Biomedicals
Synonyms:
2-(Hydroxymethyl)phenyl-β-D-glucopyranoside, Salicoside, D(-)-Salicin, (2R,3S,4S,5R,6S)-2-(Hydroxymethyl)-6-(2-(hydroxymethyl)phenoxy)tetrahydro-2H-pyran-3,4,5-triol, (2R,3S,4S,5R,6S)-2-(Hydroxymethyl)-6-[2-(hydroxymethyl)phenoxy]oxane-3,4,5-triol, D(−)-Salicin
Salicin is an alcoholic β-glucoside derived from willow bark that produces anti-inflammatory (including analgesic and antipyretic) effects very similar to that of aspirin Salicin is a substrate for β-glucosidase.
Salicin is used as an analgesic and antipyretic. It is also used as a substrate for beta-glucosidase and an inhibitor of Cox. It finds application as an anti-inflammatory agent. It is involved in antipyretic action without causing gastric injury.
Biochem/physiol Actions: It acts as a non-selective COX inhibitor, exhibiting IC50 values > 100 µM for COX-1 and COX-2.
Freely soluble in water (50 mg/ml-clear,colorless solution); soluble in alkalies, pyridine, glacial acetic acid; practically insoluble in ether and chloroform.
Formula:
C₁₃H₁₈O₇ MW: 286,28 g/mol Melting Pt: 199 - 201 °C Density: 1,42 g/cm³ (20 °C) Storage Temperature: Ambient |
MDL Number:
MFCD00006590 CAS Number: 138-52-3 EINECS: 205-331-6 Merck Index: 12,08476 |
Specification Test Results
Identity Test | Passes |
FTIR | Conforms to Standard |
194 - 204 °C | Melting Point |
Optical Rotation | −65° ± 5° (c=3, water) |
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