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Description: Insulin-like growth factors (IGFs) comprise a family of endocrine, paracrine and autocrine polypeptides consisting of the ligands IGF1 and IGF2, two receptors (IGF1R, IGF2R), at least 6 IGF-binding proteins (IGFBPs) and IGFBP proteases. Among the binding proteins, IGFBP6 is unique because of its N-terminal disulphide linkages and its marked binding preference for IGF2. It is a potent inhibitor of the interaction between IGF2 and its receptor IGF1R, thus preventing major functions of IGF2, such as induction of proliferation, differentiation, cell adhesion, or colony formation. In particular, IGFBP-6 inhibited the growth of neuroblastoma and rhabdomyosarcoma xenografts. GFBP-6 is expressed in many tissues, including lung, liver, gut and the central nervous system.
Catalog Number: PRSI92-567
UOM: 1 * 50 µG
Supplier: ProSci Inc.


Description: 5-(4-Fluorophenyl)-3-pyridinecarboxylic acid for synthesis, Sigma-Aldrich®
Catalog Number: 8.43818.0025
UOM: 1 * 25 g
Supplier: Merck

MSDS


Description: Sodium tetrakis(4-fluorophenyl)borate dihydrate is sodium salt derivative of tetraphenylborate (TPB).
Catalog Number: 72014-500MG
UOM: 1 * 500 mg
Supplier: Merck


Description: CD98 exits as a heterodimer containing a disulphide-linked glycosylated heavy chain and a non-glycosylated light chain. It is a member of the solute carrier family and encodes a cell surface, transmembrane protein. The protein exists as the heavy chain of a heterodimer, covalently bound through disulfide bonds to one of several possible light chains. The encoded transporter plays a role in regulation of intracellular calcium levels and transports L-type amino acids. Alternatively spliced transcript variants, encoding different isoforms, have been characterised.
Catalog Number: PRSI33-463
UOM: 1 * 100 µG
Supplier: ProSci Inc.


Description: CD98 exits as a heterodimer containing a disulphide-linked glycosylated heavy chain and a non-glycosylated light chain. It is a member of the solute carrier family and encodes a cell surface, transmembrane protein. The protein exists as the heavy chain of a heterodimer, covalently bound through disulfide bonds to one of several possible light chains. The encoded transporter plays a role in regulation of intracellular calcium levels and transports L-type amino acids. Alternatively spliced transcript variants, encoding different isoforms, have been characterised.
Catalog Number: PRSI33-203
UOM: 1 * 100 µG
Supplier: ProSci Inc.


Description: Nα-(2,4-Dinitro-5-fluorophenyl)-L-valinamide [L-FDVA] is a derivatizing chiral agent.
Catalog Number: 42102-100MG
UOM: 1 * 100 mg
Supplier: Merck


Description: 3-(4-Fluorophenyl)propanal
Catalog Number: APOSPC301205-1G
UOM: 1 * 1 g
Supplier: Apollo Scientific


Description: 1-(3-Fluorophenyl)propylamine
Catalog Number: APOSPC3484-250MG
UOM: 1 * 250 mg
Supplier: Apollo Scientific


Description: 2-(4-Fluorophenyl)benzofuran
Catalog Number: APOSPC440021-100MG
UOM: 1 * 100 mg
Supplier: Apollo Scientific


Description: Below 35 to 40 °C gelatin swells and absorbs approximately 5 to 10 times its weight of water to form a gel. Gelatin is soluble in glycerol and acetic acid, and more soluble in hot than in cold water. It is practically insoluble in most organic solvents such as alcohol, chloroform, carbon disulphide, carbon tetrachloride, ether, benzene, acetone and oils. Sterile solutions of gelatin stored cold are stable indefinitely, but at elevated temperatures hydrolysis or rupture of peptide bonds occurs, increasing the number of free amino groups. Gel strength and viscosity gradually weaken upon prolonged heating in solution above ~40 °C; this degradation is accelerated by extremes in pH, proteolytic enzymes and bacterial action.
Catalog Number: ICNA0296031790
UOM: 1 * 500 g
Supplier: MP Biomedicals


Description: 2-(4-Fluorophenyl)nicotinaldehyde 95%
Catalog Number: APOSPC28199-1G
UOM: 1 * 1 g
Supplier: Apollo Scientific


Description: 2-(4-Fluorophenyl)azepane 95%
Catalog Number: APOSPC904975-1G
UOM: 1 * 1 g
Supplier: Apollo Scientific


Description: 3-(2-Fluorophenyl)propionaldehyde 95%
Catalog Number: APOSPC905581-5G
UOM: 1 * 5 g
Supplier: Apollo Scientific


Description: Clusterin shares homology with the small heat shock protein family of molecular chaperones. The mature secreted form of the protein is a glycosylated, 80-kDa disulphide-linked heterodimer of alpha and beta subunits (produced by internal cleavage). Clusterin is expressed in virtually all tissues and found in all human fluids. It is involved in numerous physiological processes important for carcinogenesis and tumour growth, including apoptotic cell death, cell cycle regulation, DNA repair, cell adhesion, tissue remodelling, lipid transportation, membrane recycling, and immune system regulation. Clusterin also exists as a nuclear protein. The secreted form of Clusterin has extracellular chaperone and anti-apoptotic activities while the nuclear form acts as a proapoptotic factor.
Catalog Number: PRSI90-038
UOM: 1 * 50 µG
Supplier: ProSci Inc.


Description: (2-Fluorophenyl)glycine 97%
Catalog Number: APOSPC3964-1G
UOM: 1 * 1 g
Supplier: Apollo Scientific


Description: 1-(2-Fluorophenyl)-2-propylamine 97%
Catalog Number: H50999.03
UOM: 1 * 1 g
Supplier: Thermo Fisher Scientific

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