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Image Unavailable-BOSSBS-12544R-A750

Anti-ATIC/AICAR transformylase Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-12544R-A750)
Supplier: Bioss
Description: The bifunctional purine biosynthesis protein ATIC (also designated PURH) contains AICAR transformylase and IMP cyclohydrolase activities. AICAR (5-aminoimidazole-4-carboxamide ribonucleotide) transformylase catalyses the second to last step in purine biosynthesis, playing an important role in the production of nucleotides and IMP. Defects in the ATIC transformylase gene can cause AICA-rebsuria, also designated AICA-ribosiduria, an inborn error in purine biosynthesis that is neurologically cataclysmic. Individuals with AICA-rebosuria accumulate AICA-riboside, also designated ZMP, and its derivatives in erythrocytes and fibroblasts. Patients also excrete very large amounts of AICA-riboside in the urine. Mental retardation, epilepsy, dysmorphic features and congenital blindness are all symptoms of this disease.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12544R-A555

Anti-PURH Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-12544R-A555)
Supplier: Bioss
Description: The bifunctional purine biosynthesis protein ATIC (also designated PURH) contains AICAR transformylase and IMP cyclohydrolase activities. AICAR (5-aminoimidazole-4-carboxamide ribonucleotide) transformylase catalyzes the second to last step in purine biosynthesis, playing an important role in the production of nucleotides and IMP. Defects in the ATIC transformylase gene can cause AICA-rebsuria, also designated AICA-ribosiduria, an inborn error in purine biosynthesis that is neurologically cataclysmic. Individuals with AICA-rebosuria accumulate AICA-riboside, also designated ZMP, and its derivatives in erythrocytes and fibroblasts. Patients also excrete very large amounts of AICA-riboside in the urine. Mental retardation, epilepsy, dysmorphic features and congenital blindness are all symptoms of this disease.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12544R-A350

Anti-PURH Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-12544R-A350)
Supplier: Bioss
Description: The bifunctional purine biosynthesis protein ATIC (also designated PURH) contains AICAR transformylase and IMP cyclohydrolase activities. AICAR (5-aminoimidazole-4-carboxamide ribonucleotide) transformylase catalyzes the second to last step in purine biosynthesis, playing an important role in the production of nucleotides and IMP. Defects in the ATIC transformylase gene can cause AICA-rebsuria, also designated AICA-ribosiduria, an inborn error in purine biosynthesis that is neurologically cataclysmic. Individuals with AICA-rebosuria accumulate AICA-riboside, also designated ZMP, and its derivatives in erythrocytes and fibroblasts. Patients also excrete very large amounts of AICA-riboside in the urine. Mental retardation, epilepsy, dysmorphic features and congenital blindness are all symptoms of this disease.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12544R-FITC

Anti-PURH Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-12544R-FITC)
Supplier: Bioss
Description: The bifunctional purine biosynthesis protein ATIC (also designated PURH) contains AICAR transformylase and IMP cyclohydrolase activities. AICAR (5-aminoimidazole-4-carboxamide ribonucleotide) transformylase catalyzes the second to last step in purine biosynthesis, playing an important role in the production of nucleotides and IMP. Defects in the ATIC transformylase gene can cause AICA-rebsuria, also designated AICA-ribosiduria, an inborn error in purine biosynthesis that is neurologically cataclysmic. Individuals with AICA-rebosuria accumulate AICA-riboside, also designated ZMP, and its derivatives in erythrocytes and fibroblasts. Patients also excrete very large amounts of AICA-riboside in the urine. Mental retardation, epilepsy, dysmorphic features and congenital blindness are all symptoms of this disease.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12544R-CY3

Anti-PURH Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-12544R-CY3)
Supplier: Bioss
Description: The bifunctional purine biosynthesis protein ATIC (also designated PURH) contains AICAR transformylase and IMP cyclohydrolase activities. AICAR (5-aminoimidazole-4-carboxamide ribonucleotide) transformylase catalyzes the second to last step in purine biosynthesis, playing an important role in the production of nucleotides and IMP. Defects in the ATIC transformylase gene can cause AICA-rebsuria, also designated AICA-ribosiduria, an inborn error in purine biosynthesis that is neurologically cataclysmic. Individuals with AICA-rebosuria accumulate AICA-riboside, also designated ZMP, and its derivatives in erythrocytes and fibroblasts. Patients also excrete very large amounts of AICA-riboside in the urine. Mental retardation, epilepsy, dysmorphic features and congenital blindness are all symptoms of this disease.
UOM: 1 * 100 µl
Image Unavailable-EDQMA0350010

Organic reference standards, allopurinols, Ph. Eur.

Supplier: EDQM
Description: Organic Standard, Allopurinol impurity B, (5-formylamino-1H-pyrazole-4-carboxamide), Ph. Eur. standard

Image Unavailable-474522500.

Lenvatinib mesylate 98%

Supplier: Thermo Fisher Scientific
Description: Lenvatinib mesylate 98%

New Product

Image Unavailable-J61023.ME

Dacarbazine

Supplier: Thermo Fisher Scientific
Description: Dacarbazine

MSDS Certificates

Image Unavailable-HONCR1270-10MG

Pesticide standard, Fipronil carboxamide, reference material, Honeywell Fluka™

Catalog Number: (HONCR1270-10MG)
Supplier: Honeywell Chemicals
Description: High quality organic reference materials produced according to ISO 9001.
UOM: 1 * 10 mg
Image Unavailable-ICNA0215010301

6-Aminonicotinamide, pale yellow crystalline powder

Supplier: MP Biomedicals
Description: 6-Aminonicotinamide was found to inhibit NADP+-dependent enzyme, 6-phosphogluconate dehydrogenase.

Image Unavailable-PROOICRS0357

Nicotinamide

Catalog Number: (PROOICRS0357)
Supplier: LGC Standards PROMOCHEM
Description: Nicotinamide
UOM: 1 * 100 mg
Product Image-ACRO467891000

VE-821 95%

Catalog Number: (ACRO467891000)
Supplier: Thermo Fisher Scientific
Description: Chemical probes can be used to help establish the
relationship between a molecular target and the broader
biological consequences of modulating that target in cells
or organisms.
UOM: 1 * 100 mg
Image Unavailable-BOSSBS-12544R-CY5

Anti-PURH Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-12544R-CY5)
Supplier: Bioss
Description: The bifunctional purine biosynthesis protein ATIC (also designated PURH) contains AICAR transformylase and IMP cyclohydrolase activities. AICAR (5-aminoimidazole-4-carboxamide ribonucleotide) transformylase catalyzes the second to last step in purine biosynthesis, playing an important role in the production of nucleotides and IMP. Defects in the ATIC transformylase gene can cause AICA-rebsuria, also designated AICA-ribosiduria, an inborn error in purine biosynthesis that is neurologically cataclysmic. Individuals with AICA-rebosuria accumulate AICA-riboside, also designated ZMP, and its derivatives in erythrocytes and fibroblasts. Patients also excrete very large amounts of AICA-riboside in the urine. Mental retardation, epilepsy, dysmorphic features and congenital blindness are all symptoms of this disease.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12544R-A488

Anti-PURH Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-12544R-A488)
Supplier: Bioss
Description: The bifunctional purine biosynthesis protein ATIC (also designated PURH) contains AICAR transformylase and IMP cyclohydrolase activities. AICAR (5-aminoimidazole-4-carboxamide ribonucleotide) transformylase catalyzes the second to last step in purine biosynthesis, playing an important role in the production of nucleotides and IMP. Defects in the ATIC transformylase gene can cause AICA-rebsuria, also designated AICA-ribosiduria, an inborn error in purine biosynthesis that is neurologically cataclysmic. Individuals with AICA-rebosuria accumulate AICA-riboside, also designated ZMP, and its derivatives in erythrocytes and fibroblasts. Patients also excrete very large amounts of AICA-riboside in the urine. Mental retardation, epilepsy, dysmorphic features and congenital blindness are all symptoms of this disease.
UOM: 1 * 100 µl
Image Unavailable-PROOMM0076.00

Carbamazepine

Catalog Number: (PROOMM0076.00)
Supplier: LGC Standards PROMOCHEM
Description: Carbamazepine
UOM: 1 * 250 mg
Image Unavailable-PROOMM0385.00

Pyrazinamide

Catalog Number: (PROOMM0385.00)
Supplier: LGC Standards PROMOCHEM
Description: Pyrazinamide
UOM: 1 * 500 mg
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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