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Image Unavailable-USBI135937

Anti-CACNA2D1 Rabbit Polyclonal Antibody

Catalog Number: (USBI135937)
Supplier: US Biological
Description: Anti-CACNA2D1 Rabbit Polyclonal Antibody
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8869R-A750

Anti-IP3 Receptor Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-8869R-A750)
Supplier: Bioss
Description: Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1133R-A555

Anti-SPARC Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-1133R-A555)
Supplier: Bioss
Description: Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7067R-A680

Anti-FKBP38 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-7067R-A680)
Supplier: Bioss
Description: Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state. The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regulation of apoptosis. Homomultimers or heteromultimers (Potential). Forms heterodimer with calmodulin. When activated by calmodulin and calcium, interacts with the BH4 domain of BCL2 and weakly with BCLX isoform Bcl-X(L). Does not bind and inhibit calcineurin. Interacts with HCV NS5A. Interacts with ZFYVE27; may negatively regulate ZFYVE27 phosphorylation.Tissue specificity: Widely expressed. Highest levels seen in the brain.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1247R-CY3

Anti-GRM5 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-1247R-CY3)
Supplier: Bioss
Description: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity (By similarity).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1133R-A350

Anti-SPARC Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-1133R-A350)
Supplier: Bioss
Description: Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2654R-A488

Anti-LTB4R Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-2654R-A488)
Supplier: Bioss
Description: Receptor for extracellular ATP >UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2654R-A555

Anti-LTB4R Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-2654R-A555)
Supplier: Bioss
Description: Receptor for extracellular ATP >UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9011R-CY3

Anti-MICU2 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-9011R-CY3)
Supplier: Bioss
Description: The EF-hand domain is a twelve amino acid loop motif that is commonly found in proteins that participate in calcium-binding events within the cell. EF-hand domains generally exist in a pair that, together, form a stable four-helix bundle that enables the binding of calcium ions. EF-HA1 (EF-hand domain family, member A1) is a 434 amino acid protein that contains four EF-hand domains, suggesting a role in calcium-mediated events throughout the cell. The gene encoding EF-HA1 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome. Trisomy 13, also known as Patau syndrome, is deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2654R-A350

Anti-LTB4R Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-2654R-A350)
Supplier: Bioss
Description: Receptor for extracellular ATP >UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3552R-CY5.5

Anti-Nesfatin-1 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-3552R-CY5.5)
Supplier: Bioss
Description: Calcium-binding protein. May have a role in Calcium homeostasis. Nesfatin-1: Anorexigenic peptide, seems to play an important role in hypothalamic pathways regulating food intake and energy homeostasis, acting in a leptin-independent manner. May also exert hypertensive roles and modulate blood pressure through directly acting on peripheral arterial resistance (By similarity).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3552R-CY5

Anti-Nesfatin-1 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-3552R-CY5)
Supplier: Bioss
Description: Calcium-binding protein. May have a role in Calcium homeostasis. Nesfatin-1: Anorexigenic peptide, seems to play an important role in hypothalamic pathways regulating food intake and energy homeostasis, acting in a leptin-independent manner. May also exert hypertensive roles and modulate blood pressure through directly acting on peripheral arterial resistance (By similarity).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3552R-CY3

Anti-Nesfatin-1 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-3552R-CY3)
Supplier: Bioss
Description: Calcium-binding protein. May have a role in Calcium homeostasis. Nesfatin-1: Anorexigenic peptide, seems to play an important role in hypothalamic pathways regulating food intake and energy homeostasis, acting in a leptin-independent manner. May also exert hypertensive roles and modulate blood pressure through directly acting on peripheral arterial resistance (By similarity).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2015R-CY5.5

Anti-S100 B Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-2015R-CY5.5)
Supplier: Bioss
Description: Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5913R-CY5

Anti-CALR Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-5913R-CY5)
Supplier: Bioss
Description: Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of Calcium homeostasis (By similarity).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1133R-CY3

Anti-SPARC Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-1133R-CY3)
Supplier: Bioss
Description: Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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