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Supplier: MP Biomedicals
Description: Urea is a mild agent usually used in the solubilization and denaturation of proteins.

Supplier: MP Biomedicals
Description: Storage: Store at Room Temperature (15 - 30 °C)
Glycerol is used both in sample preparation and gel formation for polyacrylamide gel electrophoresis. Glycerol (5-10%) increases the density of a sample so that the sample will layer at the bottom of a gel’s sample well. Glycerol is also used to aid in casting gradient gels and as a protein stabilizer and storage buffer component. Glycerol is used in the concentration and storage of enzymes. Also prevents back-diffusion and protein samples into the buffer. Ideal for use as a cryoprotectant.

Supplier: MP Biomedicals
Description: Vincristine Sulfate, a dimeric Vinca alkaloid. Experiments have reported Vincristine Sulfate to demonstrate a capacity to suppress growth of proliferating cells through marked apoptosis. The cell death caused by this agent seems to result in a sustained accumulation of endogenous ceramide levels. Ceramide, has been proposed as a lipid second messenger with specific antiproliferative mediating responses.

Supplier: ENZO LIFE SCIENCES
Description: Macrocyclic-triene antibiotic possessing potent immunosuppressant activity. It forms a complex with FKBP12 that binds to an effector, thus inhibiting IL-2 and other growth promoting lymphokines. The effectors were identified as FRAP (FKBP12 rapamycin-associated protein) and RAFT1 (rapamycin and KFBP12 target). Rapamycin/FKBP complex does not inhibit FRAP PI 4-kinase activity, but does inhibit FRAP autophosphorylation. Rapamycin induces inhibition of p70<sup>s6k</sup>, p33<sup>cdk2</sup> and p34<sup>cdc2</sup>. Selectively blocks signaling leading to the activation of p70/85 S6 kinase. Enhances apoptosis. Activator of autophagy both<i> in vitro</i> and <i>in vivo</i>.

Supplier: MP Biomedicals
Description: Creatinine, the end product of creatine catabolism is a normal constituent of urine; daily output about 25 mg/kg body weight. The increased amounts in the urine are typically associated with substantially impaired renal function. Also found together with creatine in muscle tissues and blood. It reacts with picric acid under alkaline conditions to form a Janovski complex. The rate of formation of the colored complex, measured at 480-520 nm is proportional to the creatinine concentration.
Creatinine is a useful marker for normalizing levels of other molecules found in urine and the altered creatinine levels may be associated with conditions that result in decreased renal blood flow, such as diabetes and cardiovascular disease.

Supplier: MP Biomedicals
Description: Ampicillin sodium salt is a semi-synthetic derivative of penicillin, active as a broad-spectrum antibiotic. It is inactivated by beta-lactamases and for this reason a beta-lactamase inhibitor should be considered when using ampicillin. Against gram-positive bacteria, ampicillin has a similar mode of action as benzylpenicillin; against gram-negative bacteria, it has a similar mode of action as chloramphenicol and tetracyclines. In E. coli it inhibits cell wall synthesis.

Supplier: MP Biomedicals
Description: Storage: Room Temperature, desiccate, protect from light
p-Aminobenzoic acid is an aminobenzoic acid isomer that combines with pteridine and Glutamic acid to form folic acid.
p-Aminobenzoic acid is part of several cell culture media as vitamin H1. In industrial field, it is a starting material in the manufacture of target esters, salts, folic acid, azo dyes and other organic compounds. It is used as an UV-blocking ingredient in sun tan cosmetics. It is used in medical field for preparing local anesthetic and ointments.

Supplier: MP Biomedicals
Description: Methacholine chloride is a cholinergic agonist and parasympathomimetic bronchoconstrictor. A metabolically stable analog of acetylcholine. Its ability to constrict airway smooth muscle is used to assess bronchial reactivity in the laboratory and clinically.
Methacholine is primarily used to diagnose bronchial hyperreactivity, which is the hallmark of asthma and also occurs in chronic obstructive pulmonary disease. Acetyl-β-methylcholine (methacholine), an analog of acetylcholine, is use as a receptor agonist to study processes such as airway hyperresponsiveness associated with asthma.
Metabolically stable analog of acetylcholine; muscarinic agonist. Its ability to constrict airway smooth muscle is used to assess bronchial reactivity in the laboratory and clinically.

Supplier: MP Biomedicals
Description: (S)-(+)-Camptothecin binds irreversibly to the DNA-topoisomerase I complex, inhibiting the reassociation of DNA after cleavage by topoisomerase I and traps the enzyme in a covalent linkage with DNA.

Supplier: MP Biomedicals
Description: A gelling polysaccharide extracted from giant brown seaweed. It is a straight chain, colloidal, polyuronic acid composed mainly of anhydro-b-D-mannuronic acid residues linked in the 1---->4 position. It has been used in the flocculation of solids in water treatment; as sizing agent; thickener; emulsion stabilizer; and a suspending agent.
Alginate, a colloidal polyuronic acid structural molecule capable of gelation, is used in the preparation of colloidal biodegradable structures such as gels, biofilms, beads, nanoparticles, and microcapsules suitable for applications that range from gel based separation technologies to drug delivery and cell preservation.

Supplier: MP Biomedicals
Description: Urea is a prinicipal protein metabolite end product of nitrogen metabolism in most mammals, formed by the enzymatic reactions of the Kreb's cycle and the major product for the removal of free ammonia (NH4+) in vivo.

Catalog Number: (116543050.)
Supplier: MP Biomedicals
Description: Quick and convenient purification of total RNA from animal tissues, plant tissues and tissue cultures using spin column technology.
UOM: 1 * 50 Tests


Supplier: MP Biomedicals
Description: Quinine Hydrochloride is an alkaloid originally isolated from the Cinchona family of South American trees. It is an antimalarial agent, anticholinergic, antihypertensive and hypoglycemic agent.

Supplier: MP Biomedicals
Description: Urea is the principal end product of nitrogen metabolism in most mammals, formed by the enzymatic reactions of the Kreb's cycle.

Supplier: MP Biomedicals
Description: Retinoic acid (RA) is a vitamin A-derived, non-peptidic, small lipophilic molecule that mediates the functions of vitamin A required for growth and development. It affects gene transcription and modulates a wide variety of biological processes like Cell Proliferation, Differentiation, including Apoptosis. Retinoic Acid mediated gene transcription depends on the rate of transport of Retinoic Acid to target cells and the timing of exposure of Retinoic Acid to RARs (Retinoic Acid Receptors) in the target tissues

Catalog Number: (41011.)
Supplier: Biotium
Description: 6X DNA loading buffer that includes ultra-sensitive, non-toxic GelRed® dye.
UOM: 1 * 1 mL

Environmentally Preferable


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
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