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Image Unavailable-BOSSBS-11696R-A647

Anti-HAP40/F8a Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-11696R-A647)
Supplier: Bioss
Description: The Huntingtin protein contains a polyglutamine region, which leads to Huntingtin’s disease (HD) when the number of glutamine repeats exceeds thirty-five. The mutated Huntingtin protein acts within the nucleus to induce neurodegeneration by a cell-specific apoptotic mechanism. The loss of activity of the Huntingtin protein may be contributed to abnormal interactions between the mutant protein and other associated cellular proteins. Huntingtin interacts with a variety of proteins including HAP1, glyceraldehyde phosphate dehydrogenase (GAPDH), HAP40, Rab5 and HIP1. HAP40 mediates the recruitment of Huntingtin by Rab5 onto early endosomes. Specifically, this complex regulates endosome motility, which may be a key event of the pathogenetic process leading to neurodegeneration in HD.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11696R-A680

Anti-HAP40/F8a Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-11696R-A680)
Supplier: Bioss
Description: The Huntingtin protein contains a polyglutamine region, which leads to Huntingtin's disease (HD) when the number of glutamine repeats exceeds thirty-five. The mutated Huntingtin protein acts within the nucleus to induce neurodegeneration by a cell-specific apoptotic mechanism. The loss of activity of the Huntingtin protein may be contributed to abnormal interactions between the mutant protein and other associated cellular proteins. Huntingtin interacts with a variety of proteins including HAP1, glyceraldehyde phosphate dehydrogenase (GAPDH), HAP40, Rab5 and HIP1. HAP40 mediates the recruitment of Huntingtin by Rab5 onto early endosomes. Specifically, this complex regulates endosome motility, which may be a key event of the pathogenetic process leading to neurodegeneration in HD.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11696R-A750

Anti-HAP40/F8a Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-11696R-A750)
Supplier: Bioss
Description: The Huntingtin protein contains a polyglutamine region, which leads to Huntingtin's disease (HD) when the number of glutamine repeats exceeds thirty-five. The mutated Huntingtin protein acts within the nucleus to induce neurodegeneration by a cell-specific apoptotic mechanism. The loss of activity of the Huntingtin protein may be contributed to abnormal interactions between the mutant protein and other associated cellular proteins. Huntingtin interacts with a variety of proteins including HAP1, glyceraldehyde phosphate dehydrogenase (GAPDH), HAP40, Rab5 and HIP1. HAP40 mediates the recruitment of Huntingtin by Rab5 onto early endosomes. Specifically, this complex regulates endosome motility, which may be a key event of the pathogenetic process leading to neurodegeneration in HD.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11696R-HRP

Anti-HAP40/F8a Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-11696R-HRP)
Supplier: Bioss
Description: The Huntingtin protein contains a polyglutamine region, which leads to Huntingtin’s disease (HD) when the number of glutamine repeats exceeds thirty-five. The mutated Huntingtin protein acts within the nucleus to induce neurodegeneration by a cell-specific apoptotic mechanism. The loss of activity of the Huntingtin protein may be contributed to abnormal interactions between the mutant protein and other associated cellular proteins. Huntingtin interacts with a variety of proteins including HAP1, glyceraldehyde phosphate dehydrogenase (GAPDH), HAP40, Rab5 and HIP1. HAP40 mediates the recruitment of Huntingtin by Rab5 onto early endosomes. Specifically, this complex regulates endosome motility, which may be a key event of the pathogenetic process leading to neurodegeneration in HD.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11696R-CY5

Anti-HAP40/F8a Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-11696R-CY5)
Supplier: Bioss
Description: The Huntingtin protein contains a polyglutamine region, which leads to Huntingtin’s disease (HD) when the number of glutamine repeats exceeds thirty-five. The mutated Huntingtin protein acts within the nucleus to induce neurodegeneration by a cell-specific apoptotic mechanism. The loss of activity of the Huntingtin protein may be contributed to abnormal interactions between the mutant protein and other associated cellular proteins. Huntingtin interacts with a variety of proteins including HAP1, glyceraldehyde phosphate dehydrogenase (GAPDH), HAP40, Rab5 and HIP1. HAP40 mediates the recruitment of Huntingtin by Rab5 onto early endosomes. Specifically, this complex regulates endosome motility, which may be a key event of the pathogenetic process leading to neurodegeneration in HD.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11696R-FITC

Anti-HAP40/F8a Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-11696R-FITC)
Supplier: Bioss
Description: The Huntingtin protein contains a polyglutamine region, which leads to Huntingtin’s disease (HD) when the number of glutamine repeats exceeds thirty-five. The mutated Huntingtin protein acts within the nucleus to induce neurodegeneration by a cell-specific apoptotic mechanism. The loss of activity of the Huntingtin protein may be contributed to abnormal interactions between the mutant protein and other associated cellular proteins. Huntingtin interacts with a variety of proteins including HAP1, glyceraldehyde phosphate dehydrogenase (GAPDH), HAP40, Rab5 and HIP1. HAP40 mediates the recruitment of Huntingtin by Rab5 onto early endosomes. Specifically, this complex regulates endosome motility, which may be a key event of the pathogenetic process leading to neurodegeneration in HD.
UOM: 1 * 100 µl
Image Unavailable-BIRBORB24956-1

Anti-Glyceraldehyde-3-PDH Mouse monoclonal antibody

Catalog Number: (BIRBORB24956-1)
Supplier: Biorbyt
Description: Anti-Glyceraldehyde-3-PDH Mouse monoclonal antibody
UOM: 1 * 1 mg

Market Source Item This is a MarketSource item. Additional charges may apply

Image Unavailable-BIRBORB24957-1

Anti-glyceraldehyde-3-PDH Mouse Monoclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BIRBORB24957-1)
Supplier: Biorbyt
Description: Anti-glyceraldehyde-3-PDH Mouse Monoclonal Antibody (HRP (Horseradish Peroxidase))
UOM: 1 * 1 mg

Market Source Item This is a MarketSource item. Additional charges may apply

Image Unavailable-BIRBORB24837-1

Anti-glyceraldehyde-3-PDH Mouse monoclonal antibody

Catalog Number: (BIRBORB24837-1)
Supplier: Biorbyt
Description: Anti-glyceraldehyde-3-PDH Mouse monoclonal antibody
UOM: 1 * 1 mg

Market Source Item This is a MarketSource item. Additional charges may apply

Image Unavailable-BIRBORB24987-1

Anti-Glyceraldehyde-3-PDH Mouse monoclonal antibody

Catalog Number: (BIRBORB24987-1)
Supplier: Biorbyt
Description: Anti-Glyceraldehyde-3-PDH Mouse monoclonal antibody
UOM: 1 * 1 mg

Market Source Item This is a MarketSource item. Additional charges may apply

Image Unavailable-BIRBORB24832-1

Anti-glyceraldehyde-3-PDH Mouse monoclonal antibody

Catalog Number: (BIRBORB24832-1)
Supplier: Biorbyt
Description: Anti-glyceraldehyde-3-PDH Mouse monoclonal antibody
UOM: 1 * 1 mg

Market Source Item This is a MarketSource item. Additional charges may apply

Image Unavailable-PRSI92-622

E. coli recombinant tryptophan synthase alpha chain (from E. coli)

Catalog Number: (PRSI92-622)
Supplier: ProSci Inc.
Description: Tryptophan synthase is an enzyme that catalyses the final two steps in the biosynthesis of tryptophan. It is commonly found in Eubacteria, Archaebacteria, Protista, Fungi, and Plantae, but is absent from animals such as humans. Tryptophan synthase typically exists as an alpha- beta beta - alpha complex.The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate: L-serine + 1-C-(indol-3-yl)glycerol 3-phosphate = L-tryptophan + D-glyceraldehyde 3-phosphate + H₂O.The beta subunits catalyse the irreversible condensation of indole and serine to form tryptophan in a pyridoxal phosphate (PLP) dependent reaction. Their assembly into a complex leads to structural changes in both subunits resulting in reciprocal activation.
UOM: 1 * 50 µG
Image Unavailable-PRSI92-623

E. coli recombinant tryptophan synthase beta chain (from E. coli)

Catalog Number: (PRSI92-623)
Supplier: ProSci Inc.
Description: Tryptophan synthase is an enzyme that catalyses the final two steps in the biosynthesis of tryptophan. It is commonly found in Eubacteria, Archaebacteria, Protista, Fungi, and Plantae, but is absent from animals such as humans. Tryptophan synthase typically exists as an alpha- beta beta - alpha complex.The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate: L-serine + 1-C-(indol-3-yl)glycerol 3-phosphate = L-tryptophan + D-glyceraldehyde 3-phosphate + H₂O.The beta subunits catalyse the irreversible condensation of indole and serine to form tryptophan in a pyridoxal phosphate (PLP) dependent reaction. Their assembly into a complex leads to structural changes in both subunits resulting in reciprocal activation.
UOM: 1 * 50 µG
Product Image-PRSI30-388

Anti-ALDOC Rabbit Polyclonal Antibody

Catalog Number: (PRSI30-388)
Supplier: ProSci Inc.
Description: ALDOC gene is a member of the class I fructose-biphosphate aldolase gene family. ALDOC is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively.This gene encodes a member of the class I fructose-biphosphate aldolase gene family. Expressed specifically in the hippocampus and Purkinje cells of the brain, the encoded protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively.
UOM: 1 * 50 µG
Product Image-PRSI55-626

Anti-ALDOC Rabbit Polyclonal Antibody

Catalog Number: (PRSI55-626)
Supplier: ProSci Inc.
Description: This gene encodes a member of the class I fructose-biphosphate aldolase gene family. Expressed specifically in the hippocampus and Purkinje cells of the brain, the encoded protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively.
UOM: 1 * 400 µl

New Product


Product Image-PRSI5007

Anti-GAPDH Chicken Polyclonal Antibody

Catalog Number: (PRSI5007)
Supplier: ProSci Inc.
Description: GAPDH Antibody: Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) catalyzes the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD), an important energy-yielding step in carbohydrate metabolism. Recent evidence suggests that it also is involved in a number of cellular processes such as membrane fusion, phosphotransferase activity, DNA replication and repair, and nuclear RNA export. GAPDH has also been implicated in playing a role in different pathologies such as cancer progression, apoptosis, and neuronal diseases such as Alzheimer's and Huntington's disease. GAPDH is constitutively expressed at high levels in almost all tissues and cell lines making it ideal for use as a loading control marker in immunoblots.
UOM: 1 * 100 µG
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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