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Description: ICAM-2 is a 55-65 kD transmembrane glycoprotein possessing 2 extracellular Ig domains, a single transmembrane domain, and a short 26-amino acid cytoplasmic domain. ICAM-2 is expressed on most leukocytes, and is strongly expressed on vascular endothelial cells. Interactions of ICAM-2 and the integrin receptors mediate cell adhesion in a wide range of lymphocyte, monocyte, natural killer cell, and granulocyte with other cells, and play important roles in many adhesion-dependent immune and inflammation responses, such as T cell aggregation, NK-cell cytotoxicity and migration, lymphocyte recirculation, etc. Serum levels of ICAM-2 correlated significantly with the inflammatory and course sequences of trichinosis in mice and had a similar relation with blood eosinophilia. So, estimation of ICAM-2 serum levels may prove useful in diagnosis of trichinosis recent infections, and in monitoring the prognosis and response to treatment.
Catalog Number: PRSI92-575
UOM: 1 * 50 µG
Supplier: ProSci Inc.


Description: TMB is a chromogenic substrate for Horse Radish Peroxidase (HRP). MP Biolomedicals TMB Solution is a convenient, non toxic and ready to use stable chromogen solution suitable for peroxidase and pseudo-peroxidase reactions in ELISA, it provides consistent performance and sensitivity to deliver reproducible results
Catalog Number: ICNA0215234650
UOM: 1 * 50 mL
Supplier: MP Biomedicals


Description: Mouse Il10 is the prototypic member of the IL-10 cytokine family, including IL-10, IL-19, IL-20, IL-22 (IL-TIF), IL-24 and IL-26. Many viruses encode viral members of the IL-10 family, such as Epstein-Barr virus (EBV) and human cytomegalovirus (HCMV).Its main function is inhibiting the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells. Although human and mouse IL-10 are 81% identical at the nucleotide and amino acid level, mouse IL-10 is species-specific and does not act on human cells. Interestingly, Human IL-10 is active on mouse cells.
Catalog Number: PRSI91-582
UOM: 1 * 50 µG
Supplier: ProSci Inc.


Description: Excellent colorimetric substrate for detection of horseradish peroxidase labelled probes and is used with peroxidase and peroxidase coupled systems, particularly in ELISA techniques, blue result.
Catalog Number: J62143.AP
UOM: 1 * 500 mL
Supplier: Thermo Fisher Scientific

Description: ICAM-2 is a 55-65 kD transmembrane glycoprotein possessing 2 extracellular Ig domains, a single transmembrane domain, and a short 26-amino acid cytoplasmic domain. ICAM-2 is expressed on most leukocytes, and is strongly expressed on vascular endothelial cells. Interactions of ICAM-2 and the integrin receptors mediate cell adhesion in a wide range of lymphocyte, monocyte, natural killer cell, and granulocytewith other cells, and play important roles in many adhesion-dependent immune and inflammation responses, such as T cell aggregation, NK-cell cytotoxicity and migration, lymphocyte recirculation, etc. Serum levels of ICAM-2 correlated significantly with the inflammatory and course sequences of trichinosis in mice and had a similar relation with blood eosinophilia. So, estimation of ICAM-2 serum levels may prove useful in diagnosis of trichinosis recent infections, and in monitoring the prognosis and response to treatment.
Catalog Number: PRSI91-286
UOM: 1 * 50 µG
Supplier: ProSci Inc.


Description: 3,3',5,5'-Tetramethylbenzidine is suitable as peroxidase substrate for use in ELISA procedures. The substrate produces a soluble end product that is pale blue in color and can be read spectrophotometrically at 370 or 620 to 650 nm. The TMB reaction may be stopped with 2 M H<sub>2</sub>SO<sub>4</sub> (resulting in a yellow color), and read at 450 nm. A sensitive and specific reagent for the detection of blood, assay of hemoglobin, assay of peroxidases. It is useful in gel staining procedure for low levels of home-associated peroxidases and for enzyme immunoassay of horseradish peroxidase.
Catalog Number: ICNA02190277.1
UOM: 1 * 100 mg
Supplier: MP Biomedicals


Description: Interleukin-20 (IL-20) is a member of the IL-10 family of regulatory cytokines that includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences but they are dissimilar in their biological functions. IL-20 exhibits approximately 28% amino acid identity with IL-10 and 76% amino acid identity with mouse IL-20. There are two heterodimeric receptor complexes for IL-20. The first is composed of IL-20 R alpha and IL-20 R beta . The second is composed of IL-22 R and IL-20 R beta . Whereas the IL-22 R/IL-20 R beta complex is shared with IL-24, the IL-20 R alpha/IL-20 R beta complex is shared with both IL-19 and IL-24. IL-20 has been shown to initiate transduction cascades involving STAT3 and stimulates the induction of pro-inflammatory genes including TNF- alpha and MCP-1. Initial functional studies using transgenic mice suggest that IL-20 has the ability to regulate skin development. The over-expression of both human and mouse forms of IL-20 results in keratinocyte hyper-proliferation, abnormal epidermal differentiation, and neonatal lethality. In humans, IL-20 and its receptors are up-regulated in psoriatic skin, and polymorphisms in the IL-20 gene have been associated with plaque-type psoriasis. IL-20 may also have a role in hematopoiesis. It enhances the proliferation of multi-potential progenitors in vitro and increases their numbers and cell cycling status in IL-20 transgenic mice. IL-20 is also shown to suppress COX-2 and PGE2 and acts as an inhibitor of angiogenesis in model systems.
Catalog Number: PRSI91-129
UOM: 1 * 50 µG
Supplier: ProSci Inc.


Description: 2,6-Lutidine for synthesis, Sigma-Aldrich®
Catalog Number: 8.05650.0250
UOM: 1 * 250 mL
Supplier: Merck

MSDS


Description: 2,6-Xylenol for synthesis, Sigma-Aldrich®
Catalog Number: 8.03772.0250
UOM: 1 * 250 g
Supplier: Merck

MSDS


Description: 2,6-Dichloroquinone-4-chloroimide, Sigma-Aldrich®
Catalog Number: D6511-50G
UOM: 1 * 50 g
Supplier: SIGMA ALDRICH MICROSCOPY

Description: 2,6-Lutidine, Supelco®
Catalog Number: 04991-5ML-F
UOM: 1 * 5 mL
Supplier: Merck


Description: 2,6-Xylenol, Supelco®
Catalog Number: 36715-1G
UOM: 1 * 1 g
Supplier: Merck


Description: 2,6-Dichloroquinone-4-chloroimide, Supelco®
Catalog Number: 35620-10G
UOM: 1 * 10 g
Supplier: Merck


Description: 2,6-Dimethyl-4-heptanone for synthesis, Sigma-Aldrich®
Catalog Number: 8.18831.9160
UOM: 1 * 160 kg
Supplier: Merck

MSDS


Description: 2,6-Diaminopyridine for synthesis, Sigma-Aldrich®
Catalog Number: 8.03575.0100
UOM: 1 * 100 g
Supplier: Merck

MSDS


Description: Pyridine-2,6-dicarboxylic acid, Supelco®
Catalog Number: 02321-10G-F
UOM: 1 * 10 g
Supplier: Merck


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