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Image Unavailable-ANTIA91930-100

Anti-GEMIN7 Rabbit Polyclonal Antibody

Catalog Number: (ANTIA91930-100)
Supplier: ANTIBODIES.COM
Description: Anti-GEMIN7 Rabbit Polyclonal Antibody
UOM: 1 * 100 µl

New Product


Product Image-1410175.

Bulb pipettes with syringe, one mark

Catalog Number: (1410175.)
Supplier: HIRSCHMANN
Description: Glass.
UOM: 1 * 1 items
Product Image-ABNOH00008487-B01P

Anti-GEMIN2 Mouse Polyclonal Antibody

Catalog Number: (ABNOH00008487-B01P)
Supplier: Abnova
Description: Anti-GEMIN2 Mouse Polyclonal Antibody
UOM: 1 * 50 µG
Product Image-ABNOH00079833-D01P

Anti-GEMIN6 Rabbit Polyclonal Antibody

Catalog Number: (ABNOH00079833-D01P)
Supplier: Abnova
Description: Anti-GEMIN6 Rabbit Polyclonal Antibody
UOM: 1 * 100 µG
Product Image-ABNOPAB22193

Anti-GEMIN8 Rabbit Polyclonal Antibody

Catalog Number: (ABNOPAB22193)
Supplier: Abnova
Description: Rabbit polyclonal antibody raised against recombinant GEMIN8.
UOM: 1 * 100 µl
Product Image-ABNOH00079833-B01P

Anti-GEMIN6 Mouse Polyclonal Antibody

Catalog Number: (ABNOH00079833-B01P)
Supplier: Abnova
Description: Anti-GEMIN6 Mouse Polyclonal Antibody
UOM: 1 * 50 µG
Product Image-BELAF378790000

SP Bel-Art® sampling syringe

Catalog Number: (BELAF378790000)
Supplier: Bel-Art Products, a Part of SP
Description: Sample liquids by simply squeezing the bulb, submersing in liquid, and releasing to draw liquids into the syringe.
UOM: 1 * 1 items
Image Unavailable-BOSSBS-8275R-A555

Anti-GPRIN1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-8275R-A555)
Supplier: Bioss
Description: GPRIN1 may be involved in neurite outgrowth.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8276R-A350

Anti-GPRIN2 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-8276R-A350)
Supplier: Bioss
Description: G protein-coupled receptors (GPCRs) represent a large superfamily of cell-surface receptors that are involved in a multitude of physiological processes such as perception of sensory information, modulation of synaptic transmission, hormone release/actions, regulation of cell contraction/migration and cell growth/differentiation. GPCRs interact with G proteins (heterotrimeric GTPases) to synthesize intracellular second messengers, such as diacylglycerol, cyclic AMP, inositol phosphates and calcium ions. Their diverse biological functions range from vision and olfaction to neuronal and endocrine signaling and are involved in many pathological conditions. GRIN2 (G protein-regulated inducer of neurite outgrowth 2), also known as GPRIN2, is a 458 amino acid protein that is expressed in cerebellum and is thought to play a role in neurite outgrowth. GRIN2 interacts with activated G?oand G?, and is encoded by a gene that maps to human chromosome 10q11.22.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11562R-FITC

Anti-GEMIN2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-11562R-FITC)
Supplier: Bioss
Description: Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disease characterized by loss of motor neurons in the spinal cord. SMA is caused by deletion or loss-of-function mutations in the SMN (survival of motor neuron) gene. Gemin2 (formerly known as SIP1 for SMN interacting protein) associates directly with SMN and is a part of the SMN complex containing Gemin3 (a DEAD-box RNA helicase), Gemin4, Gemin5 and Gemin6, as well as several spliceosomal snRNP proteins. The SMN complex plays an essential role in splicesomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing of the nucleus. It is found in both the cytoplasm and the nucleus. The nuclear form is concentrated in subnuclear bodies called gems (Gemini of the coiled bodies). The SMN-Gemin2 complex is associated with spliceosomal snRNAs U1 and U5. Gemin2 is expressed in spinal cord. It can be induced by TGF∫ treatment and expression is high in several E-cadherin negative human carcinoma cell lines. SMN is expressed in a wide variety of tissues including brain, kidney, liver and spinal cord, and moderately in skeletal and cardiac muscle. The gene encoding Gemin2 maps to human chromosome 14q13.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13328R-HRP

Anti-GEMIN4 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-13328R-HRP)
Supplier: Bioss
Description: Gemin4 is a component of the SMN core complex which, while in the cytoplasm, plays an essential role in ribonucleoprotein (snRNP) assembly, including the biogenesis, delivery and recycling of snRNPs to the spliceosome. In the nucleus, where SMN is required for pre-mRNA splicing, Gemin4 concentrates next to coiled bodies in subnuclear structures called gems, that are highly enriched in splicosomal snRNPs, and in the nucleolus. Deletion or loss-of-function mutations in the SMN lead to the neurodegenerative disease spinal muscular atrophy (SMA). The human Gemin4 maps to chromosome 17p13.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13330R-FITC

Anti-GEMIN7 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-13330R-FITC)
Supplier: Bioss
Description: Gemin7 is a 131 amino acid protein encoded by the mouse gene Gemin7. Gemin7, along with Gemin6, is a significant component of the the large multiprotein human SMN complex. The SMN complex functions as an assembly machine for small nuclear ribonucleoproteins (snRNPs)-the major components of the spliceosome. The survival of motor neurons (SMN) protein, a product of the disease gene of the common neurodegenerative disease, spinal muscular atrophy, is also part of the SMN complex. Although Gemin6 and Gemin7 have no significant sequence similarity with Sm proteins, both adopt canonical Sm folds. Moreover, Gemin6 and Gemin7 exist as a heterodimer, and interact with each other via an interface similar to that which mediates interactions among the Sm proteins. The Gemin6/Gemin7 complex binds to Sm proteins and might help organize Sm proteins for formation of Sm rings on snRNA targets.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13333R-FITC

Anti-GEMIN6 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-13333R-FITC)
Supplier: Bioss
Description: Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disease characterized by loss of motor neurons in the spinal cord. SMA is caused by deletion or loss-of-function mutations in the SMN (Survival of Motor Neuron) gene. Gemin6, the protein product of human chromosome 2p22.2, associates directly with SMN and is a part of the SMN complex containing Gemin2, Gemin3, Gemin4 and Gemin5 as well as several spliceosomal snRNP proteins. The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing of the nucleus. The SMN complex is found in both the cytoplasm and the nucleus. The nuclear form is concentrated in subnuclear bodies called gems (Gemini of the coiled bodies).
UOM: 1 * 100 µl
Product Image-ABCAAB88979-50

Anti-SMN/Gemin 1 Mouse Polyclonal Antibody

Catalog Number: (ABCAAB88979-50)
Supplier: Abcam
Description: Mouse polyclonal to SMN/Gemin 1.
UOM: 1 * 50 µG
Image Unavailable-BOSSBS-3301R-CY7

Anti-GRIN1 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-3301R-CY7)
Supplier: Bioss
Description: NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors (By similarity).
UOM: 1 * 100 µl
Image Unavailable-SORV001-0252

O-rings for Centrifuge Bottles

Supplier: Thermo Fisher Scientific
Description: O-ring bottle, 39 ml

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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