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Product Image-241-0416

Holders for test tubes, wood

Catalog Number: (241-0416)
Supplier: HERENZ HEINZ
Description: Test tube holders made of wood.
UOM: 1 * 1 items
Image Unavailable-ORIGTA316324

Anti-GPRIN3 Rabbit Polyclonal Antibody

Catalog Number: (ORIGTA316324)
Supplier: OriGene
Description: Anti-GPRIN3 Rabbit Polyclonal Antibody
UOM: 1 * 100 µl
Product Image-KGWA4058

Accessories for Reaction Vessels

Supplier: KGW
Description: O-rings, Silicone, O-ring, silicon

Image Unavailable-BOSSBS-11562R-A647

Anti-GEMIN2 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-11562R-A647)
Supplier: Bioss
Description: Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disease characterized by loss of motor neurons in the spinal cord. SMA is caused by deletion or loss-of-function mutations in the SMN (survival of motor neuron) gene. Gemin2 (formerly known as SIP1 for SMN interacting protein) associates directly with SMN and is a part of the SMN complex containing Gemin3 (a DEAD-box RNA helicase), Gemin4, Gemin5 and Gemin6, as well as several spliceosomal snRNP proteins. The SMN complex plays an essential role in splicesomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing of the nucleus. It is found in both the cytoplasm and the nucleus. The nuclear form is concentrated in subnuclear bodies called gems (Gemini of the coiled bodies). The SMN-Gemin2 complex is associated with spliceosomal snRNAs U1 and U5. Gemin2 is expressed in spinal cord. It can be induced by TGF∫ treatment and expression is high in several E-cadherin negative human carcinoma cell lines. SMN is expressed in a wide variety of tissues including brain, kidney, liver and spinal cord, and moderately in skeletal and cardiac muscle. The gene encoding Gemin2 maps to human chromosome 14q13.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11562R-A555

Anti-GEMIN2 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-11562R-A555)
Supplier: Bioss
Description: Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disease characterized by loss of motor neurons in the spinal cord. SMA is caused by deletion or loss-of-function mutations in the SMN (survival of motor neuron) gene. Gemin2 (formerly known as SIP1 for SMN interacting protein) associates directly with SMN and is a part of the SMN complex containing Gemin3 (a DEAD-box RNA helicase), Gemin4, Gemin5 and Gemin6, as well as several spliceosomal snRNP proteins. The SMN complex plays an essential role in splicesomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing of the nucleus. It is found in both the cytoplasm and the nucleus. The nuclear form is concentrated in subnuclear bodies called gems (Gemini of the coiled bodies). The SMN-Gemin2 complex is associated with spliceosomal snRNAs U1 and U5. Gemin2 is expressed in spinal cord. It can be induced by TGF∫ treatment and expression is high in several E-cadherin negative human carcinoma cell lines. SMN is expressed in a wide variety of tissues including brain, kidney, liver and spinal cord, and moderately in skeletal and cardiac muscle. The gene encoding Gemin2 maps to human chromosome 14q13.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13330R-A555

Anti-GEMIN7 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-13330R-A555)
Supplier: Bioss
Description: Gemin7 is a 131 amino acid protein encoded by the mouse gene Gemin7. Gemin7, along with Gemin6, is a significant component of the the large multiprotein human SMN complex. The SMN complex functions as an assembly machine for small nuclear ribonucleoproteins (snRNPs)-the major components of the spliceosome. The survival of motor neurons (SMN) protein, a product of the disease gene of the common neurodegenerative disease, spinal muscular atrophy, is also part of the SMN complex. Although Gemin6 and Gemin7 have no significant sequence similarity with Sm proteins, both adopt canonical Sm folds. Moreover, Gemin6 and Gemin7 exist as a heterodimer, and interact with each other via an interface similar to that which mediates interactions among the Sm proteins. The Gemin6/Gemin7 complex binds to Sm proteins and might help organize Sm proteins for formation of Sm rings on snRNA targets.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13330R-A488

Anti-GEMIN7 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-13330R-A488)
Supplier: Bioss
Description: Gemin7 is a 131 amino acid protein encoded by the mouse gene Gemin7. Gemin7, along with Gemin6, is a significant component of the the large multiprotein human SMN complex. The SMN complex functions as an assembly machine for small nuclear ribonucleoproteins (snRNPs)-the major components of the spliceosome. The survival of motor neurons (SMN) protein, a product of the disease gene of the common neurodegenerative disease, spinal muscular atrophy, is also part of the SMN complex. Although Gemin6 and Gemin7 have no significant sequence similarity with Sm proteins, both adopt canonical Sm folds. Moreover, Gemin6 and Gemin7 exist as a heterodimer, and interact with each other via an interface similar to that which mediates interactions among the Sm proteins. The Gemin6/Gemin7 complex binds to Sm proteins and might help organize Sm proteins for formation of Sm rings on snRNA targets.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13330R-A350

Anti-GEMIN7 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-13330R-A350)
Supplier: Bioss
Description: Gemin7 is a 131 amino acid protein encoded by the mouse gene Gemin7. Gemin7, along with Gemin6, is a significant component of the the large multiprotein human SMN complex. The SMN complex functions as an assembly machine for small nuclear ribonucleoproteins (snRNPs)-the major components of the spliceosome. The survival of motor neurons (SMN) protein, a product of the disease gene of the common neurodegenerative disease, spinal muscular atrophy, is also part of the SMN complex. Although Gemin6 and Gemin7 have no significant sequence similarity with Sm proteins, both adopt canonical Sm folds. Moreover, Gemin6 and Gemin7 exist as a heterodimer, and interact with each other via an interface similar to that which mediates interactions among the Sm proteins. The Gemin6/Gemin7 complex binds to Sm proteins and might help organize Sm proteins for formation of Sm rings on snRNA targets.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13328R-A488

Anti-GEMIN4 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-13328R-A488)
Supplier: Bioss
Description: Gemin4 is a component of the SMN core complex which, while in the cytoplasm, plays an essential role in ribonucleoprotein (snRNP) assembly, including the biogenesis, delivery and recycling of snRNPs to the spliceosome. In the nucleus, where SMN is required for pre-mRNA splicing, Gemin4 concentrates next to coiled bodies in subnuclear structures called gems, that are highly enriched in splicosomal snRNPs, and in the nucleolus. Deletion or loss-of-function mutations in the SMN lead to the neurodegenerative disease spinal muscular atrophy (SMA). The human Gemin4 maps to chromosome 17p13.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8275R-HRP

Anti-GPRIN1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-8275R-HRP)
Supplier: Bioss
Description: GPRIN1 may be involved in neurite outgrowth.
UOM: 1 * 100 µl
Product Image-516-0436

Syringe filters, nylon, Puradisc™, Whatman™

Supplier: Whatman products (Cytiva)
Description: Whatman Puradisc syringe filters from Cytiva's business combine premium quality with economic efficiency. They are well suited for rapid, routine syringe filtration of samples up to 100 ml.

Product Image-612-0314

Syringes, FORTUNA® OPTIMA®, Luer tip

Supplier: Poulten & Graf
Description: Barrel and piston in Durobax® glass, without needle.

Product Image-720-2561

Fine dosage syringes, Injekt®-F Solo

Catalog Number: (720-2561)
Supplier: B. Braun
Description: PP/PE fine dosage syringes, 1 ml, green plunger, two-piece, e.g. for tuberculin, heparin and allergy testing. Smear-resistant, black graduation for ideal readability. Latex and PVC free.
UOM: 1 * 100 items

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Product Image-613-0491

Syringes, FORTUNA® OPTIMA®, record tip

Supplier: Poulten & Graf
Description: Barrel made from Durobax® glass, metal tip and interchangeable piston, no needle, autoclavable.

Product Image-241-0329

Retort rings with bosshead

Supplier: USBECK Laborgeräte
Description: Galvanised steel (8 mm Ø).

Product Image-630-1200

Ring lights, EasyLED

Supplier: SCHOTT AG Lighting and imaging
Description: The EasyLED product line integrates advanced LED illumination with control functions in a single compact device. It is the ideal standard illumination system for routine inspections and education.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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