You Searched For: Phenyl+salicylate

Catalog Number: (BOSSBS-11676R-A750)

Supplier: Bioss

Description: UCH-L1 is a member of a gene family whose products hydrolyse small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. Expression of UCH-L1 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumours. UCH-L1 is expressed in brain neurons. Examination of specific brain regions reveals expression in all areas tested, particularly in the substantia nigra. UCH-L1 represents 1 to 2% of total soluble brain protein. Its occurrence in Lewy bodies and its function in the proteasome pathway make it a compelling candidate gene in Parkinson disease. The gene which encodes UCH-L1 maps to human chromosome 4p14. The 230 amino acid human UCH-L3 protein is 54% identical to that of UCH-L1. UCH-L3 is the predominant thiol protease and has high-affinity binding sites for ubiquitin.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-11676R-A488)

Supplier: Bioss

Description: UCH-L1 is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. Expression of UCH-L1 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumors. UCH-L1 is expressed in brain neurons. Examination of specific brain regions reveals expression in all areas tested, particularly in the substantia nigra. UCH-L1 represents 1 to 2% of total soluble brain protein. Its occurrence in Lewy bodies and its function in the proteasome pathway make it a compelling candidate gene in Parkinson disease. The gene which encodes UCH-L1 maps to human chromosome 4p14. The 230 amino acid human UCH-L3 protein is 54% identical to that of UCH-L1. UCH-L3 is the predominant thiol protease and has high-affinity binding sites for ubiquitin.

UOM: 1 * 100 µl

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Catalog Number: (ANTIA304726-100)

Supplier: ANTIBODIES.COM

Description: Mouse monoclonal [5E8] antibody to Hexanoyl-Lysine adduct for WB, ICC/IF, FACS, Flow cytometry and ELISA with samples derived from species independent.

UOM: 1 * 100 µG

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Catalog Number: (PRSI26-117)

Supplier: ProSci Inc.

Description: USP18, a member of the deubiquitinating protease family of enzymes, removes ubiquitin adducts from a broad range of protein substrates.USP18, a member of the deubiquitinating protease family of enzymes, removes ubiquitin adducts from a broad range of protein substrates.

UOM: 1 * 50 µG

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Catalog Number: (393207-100)

Supplier: Merck Millipore (Oncogene)

Description: Anti-HNE-Michael Adducts, Reduced Rabbit Polyclonal Antibody

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-5164R-A647)

Supplier: Bioss

Description: DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, giving rise to DNA with a free 5' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase 2 (TOP2) active site tyrosine residue. Hydrolyzes 5'-phosphoglycolates on protruding 5' ends on DNA double-strand breaks (DSBs) due to DNA damage by radiation and free radicals. The 5'-tyrosyl DNA phosphodiesterase activity can enable the repair of TOP2-induced DSBs without the need for nuclease activity, creating a 'clean' DSB with 5'-phosphate termini that are ready for ligation. Has also 3'-tyrosyl DNA phosphodiesterase activity, but less efficiently and much slower than TDP1. May also act as a negative regulator of ETS1 and may inhibit nuclear factor-kappa-B activation.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-5164R-HRP)

Supplier: Bioss

Description: DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, giving rise to DNA with a free 5' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase 2 (TOP2) active site tyrosine residue. Hydrolyzes 5'-phosphoglycolates on protruding 5' ends on DNA double-strand breaks (DSBs) due to DNA damage by radiation and free radicals. The 5'-tyrosyl DNA phosphodiesterase activity can enable the repair of TOP2-induced DSBs without the need for nuclease activity, creating a 'clean' DSB with 5'-phosphate termini that are ready for ligation. Has also 3'-tyrosyl DNA phosphodiesterase activity, but less efficiently and much slower than TDP1. May also act as a negative regulator of ETS1 and may inhibit nuclear factor-kappa-B activation.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-11676R-CY7)

Supplier: Bioss

Description: UCH-L1 is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. Expression of UCH-L1 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumors. UCH-L1 is expressed in brain neurons. Examination of specific brain regions reveals expression in all areas tested, particularly in the substantia nigra. UCH-L1 represents 1 to 2% of total soluble brain protein. Its occurrence in Lewy bodies and its function in the proteasome pathway make it a compelling candidate gene in Parkinson disease. The gene which encodes UCH-L1 maps to human chromosome 4p14. The 230 amino acid human UCH-L3 protein is 54% identical to that of UCH-L1. UCH-L3 is the predominant thiol protease and has high-affinity binding sites for ubiquitin.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-11676R-CY5)

Supplier: Bioss

Description: UCH-L1 is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. Expression of UCH-L1 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumors. UCH-L1 is expressed in brain neurons. Examination of specific brain regions reveals expression in all areas tested, particularly in the substantia nigra. UCH-L1 represents 1 to 2% of total soluble brain protein. Its occurrence in Lewy bodies and its function in the proteasome pathway make it a compelling candidate gene in Parkinson disease. The gene which encodes UCH-L1 maps to human chromosome 4p14. The 230 amino acid human UCH-L3 protein is 54% identical to that of UCH-L1. UCH-L3 is the predominant thiol protease and has high-affinity binding sites for ubiquitin.

UOM: 1 * 100 µl

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Catalog Number: (ANTIA304725-100)

Supplier: ANTIBODIES.COM

Description: Mouse monoclonal [5D9] antibody to Hexanoyl-Lysine adduct for WB, ICC/IF, FACS, Flow cytometry, ELISA and IHC with samples derived from species independent.

UOM: 1 * 100 µG

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Catalog Number: (AATB40008)

Supplier: AAT BIOQUEST

Description: Designed for consistent and dependable results. The Amplite® lactose quantitation kit employs an enzymatic assay to determine lactose concentration, converting lactose into galactose and glucose.

UOM: 1 * 100 Tests

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Catalog Number: (SIAL22520-500G)

Supplier: Merck

Description: Selective medium for differentiating lactose fermenting and lactose non-fermenting microorganisms.

UOM: 1 * 500 g

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Catalog Number: (BOSSBS-11131R-A680)

Supplier: Bioss

Description: Alpha-lactalbumin is the B protein of lactose synthetase secreted by the mammary epithelial cells. It is a potent Ca2+-elevating and apoptosis-inducing agent with broad, yet selective, cytotoxic activity. Multimeric lactalbumin has been shown to kill all transformed, embryonic and lymphoid cells tested, but not mature epithelial elements. This suggests that milk contributes to mucosal immunity not only by furnishing antimicrobial molecules but also by policing the function of lymphocytes and epithelium. ?lactalbumin may be helpful in discovering the site of origin of metastatic breast tumours. Human lactalbumin contains 123 amino acid residues. Comparison of the 5' flanking sequences of the two Alpha-lactalbumin genes with those of five casein genes reveals the presence of a highly conserved region extending from position -140 to -110 in all seven sequences examined, suggesting a possible regulatory role in the hormonal control or tissue-specific expression of milk protein genes in the mammary gland.

UOM: 1 * 100 µl

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Supplier: Thermo Fisher Scientific

Description: Contains either Lactose or Maltodextrin excipient

MSDS Certificates

Catalog Number: (BOSSBS-11131R-A350)

Supplier: Bioss

Description: Alpha-lactalbumin is the B protein of lactose synthetase secreted by the mammary epithelial cells. It is a potent Ca2+-elevating and apoptosis-inducing agent with broad, yet selective, cytotoxic activity. Multimeric ?lactalbumin has been shown to kill all transformed, embryonic and lymphoid cells tested, but not mature epithelial elements. This suggests that milk contributes to mucosal immunity not only by furnishing antimicrobial molecules but also by policing the function of lymphocytes and epithelium. ?lactalbumin may be helpful in discovering the site of origin of metastatic breast tumors. Human lactalbumin contains 123 amino acid residues. Comparison of the 5' flanking sequences of the two Alpha-lactalbumin genes with those of five casein genes reveals the presence of a highly conserved region extending from position -140 to -110 in all seven sequences examined, suggesting a possible regulatory role in the hormonal control or tissue-specific expression of milk protein genes in the mammary gland.

UOM: 1 * 100 µl

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Catalog Number: (ICNA091006017)

Supplier: MP Biomedicals

Description: A preparation for the isolation of enteric bacilli based on the fermentation of lactose.

UOM: 1 * 500 g

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