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Catalog Number: (ENZOBMLKI1040050)
Supplier: ENZO LIFE SCIENCES
Description: Fluor de Lys® Substrate is a highly sensitive and convenient alternative to radiolabeled, acetylated histones or peptide/HPLC methods for the assay of histone deacetylases. The Fluor de Lys® Substrate, which comprises an acetylated lysine side chain, is incubated with a sample containing HDAC activity (nuclear or cellular extract, purified enzyme, bead-bound immunocomplex, etc.). Deacetylation of the substrate sensitizes the substrate so that, in a second step, treatment with the Fluor de Lys® Developer produces a fluorophore. Histone deacetylases from all known classes have been successfully assayed with the Fluor de Lys® Substrate. These include human HDACs 1, 2, 3 and 8 (class I), human HDACs 4 and 9 (class II) and the sirtuins yeast Sir2, human SIRT1 and human SIRT2 (class III; reaction must include the sirtuin substrate NAD+). The substrate is cell-permeable and serves as the basis for the HDAC Cellular Activity Assay Kit (Prod. No. BML-AK503). NOTE: Must be used in conjunction with Fluor de Lys® Developer (Prod. No. BML-KI105). Sufficient for 100-1000 assays of HDACs or sirtuins (50 µl reaction volume, 50-500 µM (substrate).
UOM: 1 * 50 µl


Supplier: ENZO LIFE SCIENCES
Description: HDAC Substrate (fluorogenic)

Catalog Number: (ENZOBMLP1280001)
Supplier: ENZO LIFE SCIENCES
Description: Fluorogenic substrate for several matrix metalloproteinases (MMPs).
UOM: 1 * 1 mg


Catalog Number: (ENZOBMLP2590001)
Supplier: ENZO LIFE SCIENCES
Description: This peptide, YIYGSFK, was derived through a random combinatorial peptide library method and is a specific and efficient substrate for the scr family of kinases. The Km of YIYGSFK for p60c-src is 55 µM.
UOM: 1 * 1 mg


Catalog Number: (ENZOBMLP2720001)
Supplier: ENZO LIFE SCIENCES
Description: This peptide, (Ac-S)-PGRRRRK-biotin, is a substrate for CDC2 kinase.
UOM: 1 * 1 mg


Catalog Number: (ENZOBMLP2640001)
Supplier: ENZO LIFE SCIENCES
Description: This peptide, Biotin-Ahx-PKTPKKAKKL, is derived from histone H1 and is a substrate for CDK5.
UOM: 1 * 1 mg


Catalog Number: (ROCKDAB-B50)
Supplier: Rockland Immunochemicals
Description: Concentrate diluent buffer for DAB membrane substrate, 10X
UOM: 1 * 50 mL


Supplier: ENZO LIFE SCIENCES
Description: Fluorogenic substrate cleaved by plasma kallikrein and kallikrein 8, but not plasmin; by papain; and by most cathepsins (cathepsins B, C/DPP-I, F, K/O2, L, L2/V, O, S, and X/Z). Ex.: 380 nm, Em.: 460 nm, although the following Ex/Em can also be used: 355,375/440,450.

Catalog Number: (ENZOBMLP2430001)
Supplier: ENZO LIFE SCIENCES
Description: This peptide, Biotin-Ahx-GGMEDIYFEFMGGKKK, identified by screening a degenerate peptide library, is a substrate for several kinases, including HER-2/c-neu/erb-B-2, Tie-2, cFMS, and cKit.
UOM: 1 * 1 mg


Supplier: Thermo Fisher Scientific
Description: 3,3',5,5'-Tetramethylbenzidine (TMB) EASY, liquid substrate
Catalog Number: (ENZOBMLP2440001)
Supplier: ENZO LIFE SCIENCES
Description: This peptide, KEAPEDLYKDFLTL, is derived from the KDR sequence and is a substrate for FGFR.
UOM: 1 * 1 mg


Catalog Number: (ENZOBMLP1570001)
Supplier: ENZO LIFE SCIENCES
Description: This peptide sequence, EFpYAEVGRSPPDPAK, was selected by phage display analysis for optimal Shp-1 and Shp-2 phosphatase activities.
UOM: 1 * 1 mg


Supplier: Thermo Fisher Scientific
Description: Magnesium oxide substrate 10x10x0.5mm, polished one side 110 orientation
Catalog Number: (41436.KT)
Supplier: Thermo Fisher Scientific
Description: Magnesium oxide substrate 10x10x0.5mm, polished two sides 100 orientation
UOM: 1 * 1 items

Catalog Number: (ENZOBMLP1310001)
Supplier: ENZO LIFE SCIENCES
Description: Fluorogenic substrate for several matrix metalloproteinases (MMPs).
UOM: 1 * 1 mg


Catalog Number: (ENZOBMLP1320500)
Supplier: ENZO LIFE SCIENCES
Description: Fluorogenic substrate for TACE (ADAM17) (between Ala-Val), as well as MMP-3, MMP-7, MMP-12, and MMP-17, but not for ADAM19, MMP-13, nor MMP-14. Similar substrates are also cleaved by ADAM10, ADAM8 and ADAM9, and MMP-1, -2, and -9. This quenched substrate is useful for TACE inhibitor screening and kinetic analysis. Ex: 328 nm, Em: 393 nm, although the following Ex/Em have been used: 320-340/400-420. Also available: OMNIMMP® Fluorogenic Control peptide (BML-P127).
UOM: 1 * 0,5 mg


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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