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2-Amino-2-methyl-butyric acid methyl ester hydrochloride 96%

Catalog Number: (APOSOR905498-1G)

Supplier: Apollo Scientific

Description: 2-Amino-2-methyl-butyric acid methyl ester hydrochloride 96%

UOM: 1 * 1 g

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EDC-HCl (N-(3-Dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride), No-Weigh™ Format, Pierce™

Catalog Number: (PIERA35391)

Supplier: Thermo Fisher Scientific

Description: Thermo Scientific Pierce EDC is a carboxyl- and amine-reactive zero-length crosslinker. EDC reacts with a carboxyl group first and forms an amine-reactive O-acylisourea intermediate that quickly reacts with an amino group to form an amide bond with release of an isourea by-product. The intermediate is unstable in aqueous solutions and so two-step conjugation procedures rely on N-hydroxysuccinimide (NHS) for stabilization. Failure to react with an amine will result in hydrolysis of the intermediate, regeneration of the carboxyl, and release of an N-substituted urea. A side reaction is the formation of an N-acylurea, which is usually restricted to carboxyls located in hydrophobic regions of proteins.

UOM: 1 * 10 mg

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