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Catalog Number: (BOSSBS-0439R-A750)
Supplier: Bioss
Description: Angiotensin Converting enzyme is involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. ACE converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilatator. ACE exists in two forms, a 170KD somatic form and a 90KD germinal form. The somatic form is expressed by endothelial cells (especially those of lung capillaries and arterioles), epithelial cells (especially in proximal renal tubules and small intestine), by some neuronal cells and variably by some macrophages and T lymphocytes. The germinal form is expressed by spermatozoa.
UOM: 1 * 100 µl


Catalog Number: (ANTIA77583-96)
Supplier: ANTIBODIES.COM
Description: Porcine Renin ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of porcine Renin in serum, plasma, tissue homogenates, and other biological fluids.
UOM: 1 * 96 Tests

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Catalog Number: (BIRBORB74187-100)
Supplier: Biorbyt
Description: Anti-Renin in preproprotein Rabbit Polyclonal Antibody
UOM: 1 * 100 µl

Market Source Item This is a MarketSource item. Additional charges may apply

Catalog Number: (ANTIA78731-96)
Supplier: ANTIBODIES.COM
Description: Mouse Renin ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of mouse Renin in serum, plasma, tissue homogenates, and other biological fluids.
UOM: 1 * 96 Tests

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Catalog Number: (ANTIA80149-96)
Supplier: ANTIBODIES.COM
Description: Rat Renin ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of rat Renin in serum, plasma, tissue homogenates, and other biological fluids.
UOM: 1 * 96 Tests

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Catalog Number: (BIRBORB41185-100)
Supplier: Biorbyt
Description: Anti-Renin in preproprotein Rabbit Polyclonal Antibody
UOM: 1 * 100 µG

Market Source Item This is a MarketSource item. Additional charges may apply

Catalog Number: (AATB13530)
Supplier: AAT BIOQUEST
Description: Renin is an enzyme that participates in the body's renin-angiotensin system (RAS) that mediates extracellular volume and arterial vasoconstriction.
UOM: 1 * 100 Tests


Catalog Number: (ANTIA9906-100)
Supplier: ANTIBODIES.COM
Description: Rabbit polyclonal antibody to Renin Receptor for WB with samples derived from human, mouse and rat.
UOM: 1 * 100 µl

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Catalog Number: (ANTIA74670-96)
Supplier: ANTIBODIES.COM
Description: Mouse Renin Receptor ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of mouse Renin Receptor in serum, plasma, tissue homogenates, and other biological fluids.
UOM: 1 * 96 Tests

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Catalog Number: (PRSI96-647)
Supplier: ProSci Inc.
Description: Renin is also known as REN and angiotensinogenase, is a circulating enzyme that participates in the body's renin-angiotensin system (RAS), and plays an essential role in the elevation of arterial blood pressure and increased sodium retention by the kidney. Renin activates the renin-angiotensin system by cleaving angiotensinogen, produced by the liver, to yield angiotensin I, which is further converted into angiotensin II by ACE, the angiotensin-converting enzyme primarily within the capillaries of the lungs. Renin is secreted from kidney cells, which are activated via signaling from the macula densa, which responds to the rate of fluid flow through the distal tubule, by decreases in renal perfusion pressure (through stretch receptors in the vascular wall), and by sympathetic nervous stimulation, mainly through beta-1 receptor activation. Renin can bind to ATP6AP2, which results in a fourfold increase in the conversion of angiotensinogen to angiotensin I over that shown by soluble renin. In addition, renin binding results in phosphorylation of serine and tyrosine residues of ATP6AP2. The level of renin mRNA appears to be modulated by the binding of HADHB, HuR and CP1 to a regulatory region in the 3' UTR. An over-active renin-angiotension system leads to vasoconstriction and retention of sodium and water. These effects lead to hypertension. Therefore, renin inhibitors can be used for the treatment of hypertension.
UOM: 1 * 100 µG


Catalog Number: (PRSI96-645)
Supplier: ProSci Inc.
Description: Renin is also known as REN and angiotensinogenase, is a circulating enzyme that participates in the body's renin-angiotensin system (RAS), and plays an essential role in the elevation of arterial blood pressure and increased sodium retention by the kidney. Renin activates the renin-angiotensin system by cleaving angiotensinogen, produced by the liver, to yield angiotensin I, which is further converted into angiotensin II by ACE, the angiotensin-converting enzyme primarily within the capillaries of the lungs. Renin is secreted from kidney cells, which are activated via signaling from the macula densa, which responds to the rate of fluid flow through the distal tubule, by decreases in renal perfusion pressure (through stretch receptors in the vascular wall), and by sympathetic nervous stimulation, mainly through beta-1 receptor activation. Renin can bind to ATP6AP2, which results in a fourfold increase in the conversion of angiotensinogen to angiotensin I over that shown by soluble renin. In addition, renin binding results in phosphorylation of serine and tyrosine residues of ATP6AP2. The level of renin mRNA appears to be modulated by the binding of HADHB, HuR and CP1 to a regulatory region in the 3' UTR. An over-active renin-angiotension system leads to vasoconstriction and retention of sodium and water. These effects lead to hypertension. Therefore, renin inhibitors can be used for the treatment of hypertension.
UOM: 1 * 100 µG


Catalog Number: (ANTIA307134-100)
Supplier: ANTIBODIES.COM
Description: Rabbit monoclonal [ARC1149] antibody to Renin for WB with samples derived from Human.
UOM: 1 * 100 µl

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Catalog Number: (BIRBORB25481-1)
Supplier: Biorbyt
Description: Anti-Rat Renin Sheep Polyclonal Antibody
UOM: 1 * 1 mg

Market Source Item This is a MarketSource item. Additional charges may apply

Catalog Number: (ANTIA323221-96)
Supplier: ANTIBODIES.COM
Description: Mouse Renin ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <em>in vitro</em> quantitative determination of mouse Renin in serum, plasma, and other biological fluids. This ELISA kit only requires 25 µl of sample volume(s).
UOM: 1 * 96 Tests

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Catalog Number: (ANTIA79687-96)
Supplier: ANTIBODIES.COM
Description: Human Renin ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of human Renin in serum, plasma, tissue homogenates, and other biological fluids.
UOM: 1 * 96 Tests

New Product


Catalog Number: (ANTIA101594-100)
Supplier: ANTIBODIES.COM
Description: Rabbit polyclonal antibody to REN for WB and ELISA with samples derived from human.
UOM: 1 * 100 µG

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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