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Product Image-MARI0895242

Square cover slips

Supplier: MARIENFELD
Description: Siliconised cover glasses made from superior quality borosilicate glass.

Product Image-AATB20001

FluoroQuest™ Anti-Fading Kit I *Optimized for Slide Imaging* (1 Kit)

Catalog Number: (AATB20001)
Supplier: AAT BIOQUEST
Description: When exposed to excitation light, fluorescence intensity of dyes decreases due to their photooxidation or other photoreactions.
UOM: 1 * 1 KIT
Product Image-HECH92101401190

Cover glasses

Supplier: GLASWARENFABRIK KARL HECHT
Description: High spectral transmission, excellent flatness, optimum resistance to chemicals.

Product Image-DANIUKSANI50ORAH

Sanibox® Lined Cardboard Clinical Waste Containers

Supplier: DANIELS HEALTHCARE LIMITED
Description: Cardboard packagings for potentially infectious waste designed in accordance with all the applicable regulations in force. It consists of a cardboard container with a 40 µm high-density polythene liner with a sliding tie.

Product Image-VWRU89094-720

VWR® StaticAway™ Anti-Static Brushes

Supplier: VWR Collection
Description: Brushes clean by dissipating static and whisking away harmful dust, lint, and dirt. Ideal for cleaning balance pans, optics, cuvettes, slides, film, microscopes, electronics, and computer monitors. The compact brush is suitable for electronic balances, providing accurate results by eliminating pan weight variances caused by static.

Product Image-730-2205

Horizontal electrophoresis system, RunOne™

Supplier: EMBITEC
Description: The ultra compact RunOne™ electrophoresis system is able to run a whole variety of gel sizes from mini to long in less than 350 ml of buffer. The power supply with selectable 25, 50 or 100 V output slides directly into the running unit. The system can run eight to 108 samples in minutes, with the separate casting system allowing up to six gels to be cast and run at the same time.

Image Unavailable-BOSSBS-11310R-A647

Anti-TCTEL1/DYNLT1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-11310R-A647)
Supplier: Bioss
Description: Dyneins are multisubunit, high molecular weight ATPases that interact with microtubules to generate force by converting the chemical energy of ATP into the mechanical energy of movement. Cytoplasmic or axonemal Dynein heavy, intermediate, light and light-intermediate chains are all components of minus end-directed motors; the complex transports cellular cargos towards the central region of the cell. Axonemal Dynein motors contain one to three non-identical heavy chains and cause a sliding of microtubules in the axonemes of cilia and flagella in a mechanism necessary for cilia to beat and propel the cell. Cytoplasmic Dynein is an approximately 12 subunit complex of two heavy chains, two intermediate chains to anchor Dynein to its cargo, four smaller intermediate chains and several light chains. It performs functions necessary for cell survival such as organelle transport and centrosome assembly. The carboxy terminus of Dynein is important for microtubule-dependent motility and is highly conserved, while the amino terminal regions are more variable. Tctex1 is a cytoplasmic dynein light chain found in a complex with Na+ CP type X?(SCN10A). Tctex1, also designated CW-1 or TCTEL1 is expressed in heart, placenta, skeletal muscle, kidney, pancreas, spleen, prostate, testis, ovary, ileum and colon. Several proteins regulate Dynein activity, including dynactin, LIS1 and NudEL(NudE-like).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11310R-A680

Anti-TCTEL1/DYNLT1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-11310R-A680)
Supplier: Bioss
Description: Dyneins are multisubunit, high molecular weight ATPases that interact with microtubules to generate force by converting the chemical energy of ATP into the mechanical energy of movement. Cytoplasmic or axonemal Dynein heavy, intermediate, light and light-intermediate chains are all components of minus end-directed motors; the complex transports cellular cargos towards the central region of the cell. Axonemal Dynein motors contain one to three non-identical heavy chains and cause a sliding of microtubules in the axonemes of cilia and flagella in a mechanism necessary for cilia to beat and propel the cell. Cytoplasmic Dynein is an approximately 12 subunit complex of two heavy chains, two intermediate chains to anchor Dynein to its cargo, four smaller intermediate chains and several light chains. It performs functions necessary for cell survival such as organelle transport and centrosome assembly. The carboxy terminus of Dynein is important for microtubule-dependent motility and is highly conserved, while the amino terminal regions are more variable. Tctex1 is a cytoplasmic dynein light chain found in a complex with Na⁺ CP type X(SCN10A). Tctex1, also designated CW-1 or TCTEL1 is expressed in heart, placenta, skeletal muscle, kidney, pancreas, spleen, prostate, testis, ovary, ileum and colon. Several proteins regulate Dynein activity, including dynactin, LIS1 and NudEL(NudE-like).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11310R-HRP

Anti-TCTEL1/DYNLT1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-11310R-HRP)
Supplier: Bioss
Description: Dyneins are multisubunit, high molecular weight ATPases that interact with microtubules to generate force by converting the chemical energy of ATP into the mechanical energy of movement. Cytoplasmic or axonemal Dynein heavy, intermediate, light and light-intermediate chains are all components of minus end-directed motors; the complex transports cellular cargos towards the central region of the cell. Axonemal Dynein motors contain one to three non-identical heavy chains and cause a sliding of microtubules in the axonemes of cilia and flagella in a mechanism necessary for cilia to beat and propel the cell. Cytoplasmic Dynein is an approximately 12 subunit complex of two heavy chains, two intermediate chains to anchor Dynein to its cargo, four smaller intermediate chains and several light chains. It performs functions necessary for cell survival such as organelle transport and centrosome assembly. The carboxy terminus of Dynein is important for microtubule-dependent motility and is highly conserved, while the amino terminal regions are more variable. Tctex1 is a cytoplasmic dynein light chain found in a complex with Na+ CP type X?(SCN10A). Tctex1, also designated CW-1 or TCTEL1 is expressed in heart, placenta, skeletal muscle, kidney, pancreas, spleen, prostate, testis, ovary, ileum and colon. Several proteins regulate Dynein activity, including dynactin, LIS1 and NudEL(NudE-like).
UOM: 1 * 100 µl
Product Image-BOSSBS-3804R

Anti-MSH6 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-3804R)
Supplier: Bioss
Description: Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS alpha, which binds to DNA mismatches thereby initiating DNA repair. When bound, MutS alpha bends the DNA helix and shields approximately 20 base pairs, and recognizes single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. ATP binding and hydrolysis play a pivotal role in mismatch repair functions. The ATPase activity associated with MutS alpha regulates binding similar to a molecular switch: mismatched DNA provokes ADP-->ATP exchange, resulting in a discernible conformational transition that converts MutS alpha into a sliding clamp capable of hydrolysis-independent diffusion along the DNA backbone. This transition is crucial for mismatch repair. MutS alpha may also play a role in DNA homologous recombination repair. Recruited on chromatin in G1 and early S phase via its PWWP domain that specifically binds trimethylated 'Lys-36' of histone H3 (H3K36me3): early recruitment to chromatin to be replicated allowing a quick identification of mismatch repair to initiate the DNA mismatch repair reaction.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0758R-FITC

Anti-MSH2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-0758R-FITC)
Supplier: Bioss
Description: Component of the post-replicative DNA mismatch repair system (MMR). Forms two different heterodimers: MutS alpha (MSH2-MSH6 heterodimer) and MutS beta (MSH2-MSH3 heterodimer) which binds to DNA mismatches thereby initiating DNA repair. When bound, heterodimers bend the DNA helix and shields approximately 20 base pairs. MutS alpha recognizes single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA. MutS beta recognizes larger insertion-deletion loops up to 13 nucleotides long. After mismatch binding, MutS alpha or beta forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. ATP binding and hydrolysis play a pivotal role in mismatch repair functions. The ATPase activity associated with MutS alpha regulates binding similar to a molecular switch: mismatched DNA provokes ADP-->ATP exchange, resulting in a discernible conformational transition that converts MutS alpha into a sliding clamp capable of hydrolysis-independent diffusion along the DNA backbone. This transition is crucial for mismatch repair. MutS alpha may also play a role in DNA homologous recombination repair. In melanocytes may modulate both UV-B-induced cell cycle regulation and apoptosis.
UOM: 1 * 100 µl
Image Unavailable-EDWAA37317984

Rotary Vane Vacuum Pump

Supplier: EDWARDS HIGH VACUUM METTLER
Description: The E1M18 and E2M18 pumps are direct drive, sliding vane pumps. The E1M18 is a single-stage pump, and the E2M18 is a two-stage pump. The pump is oil sealed and designed for reliable, long-term operation in both laboratory and industrial environments. The pump is a freestanding unit with the drive provided through a flexible coupling by either a single-phase or three-phase (four-pole) motor.

Product Image-630-2746

Cover glasses

Catalog Number: (630-2746)
Supplier: GLASWARENFABRIK KARL HECHT
Description: Cover glasses with controlled thickness.
UOM: 1 * 1.000 items
Image Unavailable-ICNA0210269125

Poly-L-lysine hydrobromide, MP Biomedicals

Supplier: MP Biomedicals
Description: Poly-L-lysine is a positively charged amino acid polymer. Poly-lysine binds to DNA, red cell membrane and any negatively charged protein. It is typically used as a coating substrate for culture dishes, slides, etc. It enhances electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. When adsorbed to the culture surface, poly-lysine increases the number of positively charged sites available for cell binding.

Product Image-631-0673

Haemacytometer cover glasses

Supplier: MARIENFELD
Description: These rectangular cover slips for counting chambers are available in three different formats.

Product Image-11047600.

VWR® Q Path® Stick on (Cell adhesive) for Microscopy

Catalog Number: (11047600.)
Supplier: VWR Chemicals
Description: Glue for improving adherance of histologicals sections to slides. Alternative to albumin-glycerol.
UOM: 1 * 500 mL

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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The original product is no longer available. The replacement shown is available.
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