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Product Image-PRSI30-360

Anti-PDHA1 Rabbit Polyclonal Antibody

Catalog Number: (PRSI30-360)
Supplier: ProSci Inc.
Description: The pyruvate dehydrogenase complex is a nuclear-encoded mitochondrial matrix multienzyme complex that provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle by catalyzing the irreversible conversion of pyruvate into acetyl-CoA. The PDH complex is composed of multiple copies of 3 enzymes: E1 (PDHA1); dihydrolipoyl transacetylase (DLAT); and dihydrolipoyl dehydrogenase (DLD). The E1 enzyme is a heterotetramer of 2 alpha and 2 beta subunits. The E1-alpha subunit contains the E1 active site and plays a key role in the function of the PDH complex.The pyruvate dehydrogenase complex is a nuclear-encoded mitochondrial matrix multienzyme complex that provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle by catalyzing the irreversible conversion of pyruvate into acetyl-CoA. The PDH complex is composed of multiple copies of 3 enzymes: E1 (PDHA1); dihydrolipoyl transacetylase (DLAT; MIM 608770) (E2; EC 2.3.1.12); and dihydrolipoyl dehydrogenase (DLD; MIM 238331) (E3; EC 1.8.1.4). The E1 enzyme is a heterotetramer of 2 alpha and 2 beta subunits. The E1-alpha subunit contains the E1 active site and plays a key role in the function of the PDH complex (Brown et al., 1994 [PubMed 7853374]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
UOM: 1 * 100 µG
Product Image-PRSI30-359

Anti-PDHA1 Rabbit Polyclonal Antibody

Catalog Number: (PRSI30-359)
Supplier: ProSci Inc.
Description: The pyruvate dehydrogenase complex is a nuclear-encoded mitochondrial matrix multienzyme complex that provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle by catalyzing the irreversible conversion of pyruvate into acetyl-CoA. The PDH complex is composed of multiple copies of 3 enzymes: E1 (PDHA1); dihydrolipoyl transacetylase (DLAT); and dihydrolipoyl dehydrogenase (DLD). The E1 enzyme is a heterotetramer of 2 alpha and 2 beta subunits. The E1-alpha subunit contains the E1 active site and plays a key role in the function of the PDH complex.The pyruvate dehydrogenase complex is a nuclear-encoded mitochondrial matrix multienzyme complex that provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle by catalyzing the irreversible conversion of pyruvate into acetyl-CoA. The PDH complex is composed of multiple copies of 3 enzymes: E1 (PDHA1); dihydrolipoyl transacetylase (DLAT; MIM 608770) (E2; EC 2.3.1.12); and dihydrolipoyl dehydrogenase (DLD; MIM 238331) (E3; EC 1.8.1.4). The E1 enzyme is a heterotetramer of 2 alpha and 2 beta subunits. The E1-alpha subunit contains the E1 active site and plays a key role in the function of the PDH complex (Brown et al., 1994 [PubMed 7853374]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
UOM: 1 * 100 µG

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Image Unavailable-PRSI91-203

Human recombinant FGF21 (from E. coli)

Catalog Number: (PRSI91-203)
Supplier: ProSci Inc.
Description: Fibroblast Growth Factor 21 (FGF21) is a growth factor that belongs to the FGF family. FGF family proteins play a central role during prenatal development and postnatal growth and regeneration of mamy tissues, by promoting cellular proliferation and differentiation. FGF21 is a potent activator of glucose uptake on adipocytes, protects animal from diet-induced obesity when overexpression in transgenic mice, and lower blood glucose and triglyceride levels when therapeutically adiministered to diabetic redents. FGF21 is produced by hepatocytes in reponse to free fatty acid stimulation of a PPARa/RXR dimeric complex. This situation occurs clinically during starvation, or following the ingestionof a highly-fat/low-carbohydrate diet.Upon FGF21 secretion, white adipose tissue is induced to release free fatty acids from triglyceride stores. Once free fatty acid reach hepatocytes, they are oxidized and reduced to acetyl-CoA. The acetyl-CoA is recombined into 4-carbon ketone bodies, release, and transported to peripheral tissue for TCA processing and energy generation.
UOM: 1 * 50 µG
Image Unavailable-ICNA0219473425

Sodium pyruvate ≥99%, white powder cell culture reagent

Supplier: MP Biomedicals
Description: Storage: +4 °C
Pyruvic acid is an intermediate in sugar metabolism and in enzymatic carbohydrate degradation (alcoholic fermentation) where it is converted to acetaldehyde and CO2 by carboxylase. In muscle, pyruvic acid (derived from glycogen) is reduced to lactic acid during exertion, which is reoxidized and partially retransformed to glycogen during rest. It improves coliform recovery when present in culture medium. It is involved in a metabolic regulatory pathway activated by mitochondrial oxidants. Pyruvate is involved in respiratory regulation in plants by interacting with alternative oxidase at a conserved cysteine residue. It may help prevent hydrogen peroxide mediated cell death.
Sodium pyruvate is utilized as a component in culture broth and media. Sodium pyruvate is used in Wallen fermentation medium to enhance the conversion of oleic acid to 10-ketostearic acid by Bacillus sphaericus. Sodium pyruvate has also been used to establish stably transfected human B cell lines.
Sodium Pyruvate has shown antioxidant properties and protective effects against oxygen radicals. Pyruvate is produced as part of glycolysis and is an intermediate in many metabolic pathways. It can be converted into acetyl CoA and enter the TCA Cycle.

Product Image-720-0593

Multi-panel drug tests

Supplier: SURESCREEN
Description: These multipanel drugs tests can detect up to 12 drugs simultaneously.

Image Unavailable-BOSSBS-11228R-A647

Anti-JUNB Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-11228R-A647)
Supplier: Bioss
Description: Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5'-TGA[CG]TCA-3'.
UOM: 1 * 100 µl
Product Image-85051.0500

VWR® Dehydrated Culture Media, Powdered

Supplier: VWR Chemicals
Description: A range of culture media in compliance with ISO standards and the International Harmonised Pharmacopoeia. All our media are, as you would expect, produced using high quality raw materials and are subject to strict quality controls, in a production environment following Good Manufacturing Practice guidelines. Raw materials are selected in compliance with the required standards. Dehydrated culture media should be stored at 10 to 30 °C unless otherwise stated, in their closed containers in a dry environment. Standard pack size is 500 g.

MSDS Certificates

Image Unavailable-BOSSBS-5458R-CY3

Anti-JUN Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-5458R-CY3)
Supplier: Bioss
Description: Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3210R-A750

Anti-c-Jun Ser63 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-3210R-A750)
Supplier: Bioss
Description: Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0670R-A350

Anti-JUN Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-0670R-A350)
Supplier: Bioss
Description: Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11228R-FITC

Anti-JUNB Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-11228R-FITC)
Supplier: Bioss
Description: Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5'-TGA[CG]TCA-3'.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11228R-A750

Anti-JunB Thr102 + Thr104 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-11228R-A750)
Supplier: Bioss
Description: Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5'-TGA[CG]TCA-3'.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11228R-A350

Anti-JUNB Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-11228R-A350)
Supplier: Bioss
Description: Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5'-TGA[CG]TCA-3'.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11228R-CY5

Anti-JUNB Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-11228R-CY5)
Supplier: Bioss
Description: Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5'-TGA[CG]TCA-3'.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11228R-CY3

Anti-JUNB Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-11228R-CY3)
Supplier: Bioss
Description: Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5'-TGA[CG]TCA-3'.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5458R-A680

Anti-c-Jun Thr91 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-5458R-A680)
Supplier: Bioss
Description: Transcription factor that Recognises and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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