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17-Octadecynoic acid

Supplier: Cayman Chemical
Description: 17-Octadecynoic acid

Image Unavailable-CAYM17870-1

CCVJ ≥95%

Supplier: Cayman Chemical
Description: CCVJ is a fluorescent molecular rotor characterised by low background fluorescence, low fluorescence anisotropy, and good water solubility. Fluorescent molecular rotors are molecules whose fluorescence is inversely proportional to its intramolecular rotation.

Image Unavailable-CAYM19083-5

NF-κB Activation Inhibitor III ≥99%

Supplier: Cayman Chemical
Description: NF-κB Activation Inhibitor III ≥99%

Image Unavailable-CAYM12095-1

Butyrolactone 3 ≥95%, crystalline solid

Supplier: Cayman Chemical
Description: Butyrolactone 3 specifically inhibits the histone acetyltransferase Gcn5 with an IC50 value of 100 μM and has an affinity to the Gcn5 enzyme comparable to that of its natural substrate, histone H3. Butyrolactone 3 can inhibit pre-RNA splicing with an IC50 value of 0,5 mM and as such has been used to investigate Gcn5/PCAF-like HAT functions during assembly of spliceosome before pre-mRNA translation.

Image Unavailable-CAYM15260-1

Q-VD-OPh

Supplier: Cayman Chemical
Description: Q-VD-OPH is a broad-spectrum caspase inhibitor, blocking caspases-3, -7, -8, -9, -10, and -12 and inhibiting apoptosis when used at 10 µm. It more effectively inhibits apoptosis and is much less cytotoxic than Z-VAD-FMK and Boc-D-FMK.

Image Unavailable-CAYM14647-500

(-)-Indolactam V ≥97%, solid

Supplier: Cayman Chemical
Description: (−)-Indolactam V is a tumor-promoting teleocidin compound that activates protein kinase C (PKC). It binds to PKC regulatory domains of mouse skin PKCη and rat brain PKCγ with Ki values of 3,4 nM and 1 μM, respectively. At 1 μM, (−)-indolactam V induces differentiation of human embryonic stem cells into pancreatic progenitors through activation of PKC signaling.

Image Unavailable-CAYM13926-1

Anti-I kappaB-zeta Rabbit Polyclonal Antibody

Catalog Number: (CAYM13926-1)
Supplier: Cayman Chemical
Description: Anti-I kappaB-zeta Rabbit Polyclonal Antibody
UOM: 1 * 1 items
Image Unavailable-CAYM14409-1

Amiloride hydrochloride ≥98%

Supplier: Cayman Chemical
Description: Amiloride is a potassium-sparing diuretic that promotes the loss of sodium and water from the body by directly blocking sodium reabsorption through epithelial sodium channels. Amiloride can also block Na<sup>+</sup>/H<sup>+</sup> exchangers in the heart, which can serve to minimize reperfusion injury in ischemic attacks. Additionally, acid-sensing ion channels, which are involved in nociceptor responses to pH, can also be inhibited by amiloride.

Certificates

Image Unavailable-CAYM10007129-1

tert-Butyl 4-(bromomethyl)benzoate

Catalog Number: (CAYM10007129-1)
Supplier: Cayman Chemical
Description: tert-Butyl-4-(bromomethyl)benzoate
UOM: 1 * 1 g
Image Unavailable-CAYM29363-5

Long-Chain Cis/Trans Isomer Fatty Acid Methyl Ester Mixture

Catalog Number: (CAYM29363-5)
Supplier: Cayman Chemical
Description: Long-chain cis/trans isomer fatty acid methyl ester mixture contains cis and trans isomers of several fatty acids. It is intended for use as a reference standard for the detection of long-chain fatty acids in various sample types by GC-MS.
UOM: 1 * 5 mL

New Product


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Human recombinant Renin

Catalog Number: (CAYM10006217-25)
Supplier: Cayman Chemical
Description: Renin is an aspartyl protease of approximately 40 kDa produced in the kidney by juxtaglomerular cells of the macula densa.
UOM: 1 * 25 µG

Certificates


Image Unavailable-CAYM89910-500

2,6-Di-tert-butyl-p-cresol

Supplier: Cayman Chemical
Description: 2,6-Di-tert-butyl-p-cresol

Image Unavailable-CAYM10005455-10

N-Arachidonoyl-L-Serine 1% in ethanol , 98%

Catalog Number: (CAYM10005455-10)
Supplier: Cayman Chemical
Description: Arachidonoyl amides of both amino acids and neurotransmitters such as dopamine have been previously reported in the literature.
(1)N-Arachidonoyl-L-serine (ARA-S) is one such recently isolated endocannabinoid with an unusual activity profile. ARA-S does not bind to central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors or vanilloid receptor 1 (VR1). Like cannabidiol, ARA-S (5 mg/kg) antagonizes the hypotensive effects of a 10 mg/kg IV bolus of abnormal cannabidiol (Abn-CBD) in an anesthetized rat blood pressure model.
(2)However, similar to Abn-CBD, ARA-S relaxes isolated rat mesenteric arteries and abdominal aorta as well as increases phosphorylation of Akt and mitogen-activated protein kinase (MAPK) in HUVEC.
(3)The precise mechanisms of action by ARA-S and Abn-DBD in various vascular preparations appears to be different and requires further investigation.
UOM: 1 * 10 mg
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Resolvin D1 ELISA kit

Catalog Number: (CAYM500380-480)
Supplier: Cayman Chemical
Description: For the quantification of RvD1.
UOM: 1 * 480 Tests
Product Image-CAYM601010-1

NETosis Assay Kit

Catalog Number: (CAYM601010-1)
Supplier: Cayman Chemical
Description: For the measurement of NET-derived neutrophil elastase.
UOM: 1 * 1 items
Product Image-CAYM22817-50

Human recombinant TBK1 (from Baculovirus (Insect cells))

Catalog Number: (CAYM22817-50)
Supplier: Cayman Chemical
Description: Human recombinant TBK1 (from Baculovirus (Insect cells))
UOM: 1 * 50 µG
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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