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Image Unavailable-BOSSBS-5777R-A680

Anti-Activin A Receptor Type IC Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-5777R-A680)
Supplier: Bioss
Description: Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0223R-A680

Anti-MEK2 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-0223R-A680)
Supplier: Bioss
Description: catalyses the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates the ERK1 and ERK2 MAP kinases (By similarity).
UOM: 1 * 100 µl
Image Unavailable-APOSOR9986-500G

(±)-2-Aminobutyric acid

Supplier: Apollo Scientific
Description: (±)-2-Aminobutyric acid

Product Image-ACRO125310010

(±)-Mandelic acid 99+%

Supplier: Thermo Fisher Scientific
Description: (±)-Mandelic acid 99+%

MSDS

Image Unavailable-BOSSBS-3535R-CY7

Anti-PLK1 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-3535R-CY7)
Supplier: Bioss
Description: PLK1 (polo-like kinase 1) is a member of the serine/threonine protein kinase family, cdc5/polo subfamily. PLK1 contains two polo box domains with a predicted molecular weight of 68 kDa. PLK1 has been shown to regulate cdc2/cyclin B through phosphorylation and activation of cdc25c phosphatase. PLK1 is modified by phosphorylation at Threonine 210. PLK1 may also be required for cell division. Depletion of PLK1 results in apoptosis and deregulation of expression of PKL1 is correlated with development of many malignancies.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7850R-CY3

Anti-TTK Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-7850R-CY3)
Supplier: Bioss
Description: Phosphorylates proteins on serine, threonine, and tyrosine. Probably associated with cell proliferation. Essential for chromosome alignment by enhancing AURKB activity (via direct CDCA8 phosphorylation) at the centromere, and for the mitotic checkpoint.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0223R-FITC

Anti-MAP2K2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-0223R-FITC)
Supplier: Bioss
Description: Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates the ERK1 and ERK2 MAP kinases (By similarity).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4123R-CY5

Anti-MAP2K3 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-4123R-CY5)
Supplier: Bioss
Description: Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4123R-CY5.5

Anti-MAP2K3 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (BOSSBS-4123R-CY5.5)
Supplier: Bioss
Description: Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11990R-CY7

Anti-MAK Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (BOSSBS-11990R-CY7)
Supplier: Bioss
Description: The HUNK (hormonally upregulated Neu-associated kinase) protein, also designated MAK-V in mouse, has been identified as a novel SNF1-related serine/threonine kinase. The human HUNK gene localizes to chromosome 21q22 and encodes a protein with nucleocytoplasmic distribution and localizes to the centrosome. Overexpression of the HUNK protein associates with approximately 50% of breast carcinomas, and may provide diagnostic-prognostic value as a molecular marker. Serine/threonine-protein kinase SNF1-like kinase 2 (SIK) phosphorylates Ser-794 of IRS1 in insulin-stimulated adipocytes, which may modulate the efficiency of insulin signal transduction. SIK is activated by phosphorylation on Thr-175 by STK11 in complex with STE20-related adapter-α and CAB39.
UOM: 1 * 100 µl
Image Unavailable-BWRLBS4717

Anti-p-Ezrin Rabbit Polyclonal Antibody [clone: T567/Radixin]

Catalog Number: (BWRLBS4717)
Supplier: Bioworld Technology
Description: Synthetic phosphopeptide derived from human Ezrin, Radixin, Moesin respectively are around the phosphorylation site of Threonine 567, 564, 558.
UOM: 1 * 100 µG
Image Unavailable-BOSSBS-4123R-HRP

Anti-MAP2K3 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-4123R-HRP)
Supplier: Bioss
Description: Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38.
UOM: 1 * 100 µl
Image Unavailable-BWRLBS4703

Anti-p-LIMK1/2 Rabbit Polyclonal Antibody [clone: T508/505]

Catalog Number: (BWRLBS4703)
Supplier: Bioworld Technology
Description: Synthetic phosphopeptide derived from human LIMK1 around the phosphorylation site of Threonine 508.
UOM: 1 * 100 µG
Image Unavailable-J63709.30

L-Threonine cell culture reagent

Supplier: Thermo Fisher Scientific
Description: L-Threonine cell culture reagent

MSDS Certificates

Image Unavailable-BOSSBS-5537R-A647

Anti-PDPK1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-5537R-A647)
Supplier: Bioss
Description: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5545R-A488

Anti-PDPK1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-5545R-A488)
Supplier: Bioss
Description: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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