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Image Unavailable-BOSSBS-0223R-A750

Anti-MEK2 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-0223R-A750)
Supplier: Bioss
Description: catalyses the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates the ERK1 and ERK2 MAP kinases (By similarity).
UOM: 1 * 100 µl
Image Unavailable-ENZOADI905648100

Anti-JNK2 Mouse Monoclonal Antibody [clone: 12C5]

Catalog Number: (ENZOADI905648100)
Supplier: ENZO LIFE SCIENCES
Description: The Stress-activated protein kinases alpha and gamma (SAPKalpha and gamma), also know as c-Jun NH2-terminal kinases 1 and 2 (Jnk1/2) are serine/ threonine protein kinases belonging to the MAP kinase family. The extracellular stimuli leading to cell stress include inflammatory cytokines (via Rho and Rac), growth factors, protein synthesis inhibitors and osmotic stress amongst others. Both Jnk1 and Jnk2 must be dually phosphorylated in the activation loop, at threonine 183 and tyrosine 185, to achieve full enzymatic activity.
UOM: 1 * 100 µG
Image Unavailable-ENZOADI905650100

Anti-JNK3 Mouse Monoclonal Antibody [clone: 4G6]

Catalog Number: (ENZOADI905650100)
Supplier: ENZO LIFE SCIENCES
Description: The Stress-activated protein kinases alpha and gamma (SAPKalpha and gamma), also known as c-Jun NH2-terminal kinases 1 and 2 (Jnk1/2) are serine/ threonine protein kinases belonging to the MAP kinase family. The extracellular stimuli leading to cell stress include inflammatory cytokines (via Rho and Rac), growth factors, protein synthesis inhibitors and osmotic stress amongst others. Both Jnk1 and Jnk2 must be dually phosphorylated in the activation loop, at threonine 183 and tyrosine 185, to achieve full enzymatic activity.
UOM: 1 * 100 µG
Image Unavailable-BOSSBS-5544R

Anti-PDPK1 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-5544R)
Supplier: Bioss
Description: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5545R-CY5

Anti-PDPK1 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-5545R-CY5)
Supplier: Bioss
Description: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.
UOM: 1 * 100 µl
Image Unavailable-BWRLBS4057

Anti-p-Cyclin E1 Rabbit Polyclonal Antibody [clone: T395]

Catalog Number: (BWRLBS4057)
Supplier: Bioworld Technology
Description: Synthetic phosphopeptide derived from human Cyclin E1 around the phosphorylation site of Threonine 395.
UOM: 1 * 100 µG
Image Unavailable-BWRLBS4782

Anti-p-DARPP-32 Rabbit Polyclonal Antibody [clone: T34]

Catalog Number: (BWRLBS4782)
Supplier: Bioworld Technology
Description: Synthetic phosphopeptide derived from human DARPP-32 around the phosphorylation site of Threonine 34.
UOM: 1 * 100 µG
Image Unavailable-BOSSBS-4123R-A680

Anti-MEK3 Thr222 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-4123R-A680)
Supplier: Bioss
Description: Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. catalyses the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38.
UOM: 1 * 100 µl
Product Image-ACRO172090250

(±)-2-Aminobutyric acid 99%

Supplier: Thermo Fisher Scientific
Description: (±)-2-Aminobutyric acid 99%

MSDS Certificates

Image Unavailable-BWRLBS5016

Anti-p-ERK1/2 Rabbit Polyclonal Antibody [clone: T202/Y204]

Catalog Number: (BWRLBS5016)
Supplier: Bioworld Technology
Description: Synthetic phosphopeptide derived from human ERK1/2 around the phosphorylation site of Threonine 202/Tyrosine 204.
UOM: 1 * 100 µG
Image Unavailable-BOSSBS-3275R

Anti-MAP2K6 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-3275R)
Supplier: Bioss
Description: Mitogen activated protein kinase kinase 6 (MEK6 or MKK6) belongs to the serine/threonine protein kinase family and the MAPK kinase subfamily (MAP2K, MKK or MEKs). MEK6, closely related to MEK3, catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in MAP kinase p38, thus activating it, in response to inflammatory cytokines and environmental stress.As an essential component of p38 MAP kinase mediated signal transduction pathway, this protein is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3275R-CY3

Anti-MAP2K6 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-3275R-CY3)
Supplier: Bioss
Description: Mitogen activated protein kinase kinase 6 (MEK6 or MKK6) belongs to the serine/threonine protein kinase family and the MAPK kinase subfamily (MAP2K, MKK or MEKs). MEK6, closely related to MEK3, catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in MAP kinase p38, thus activating it, in response to inflammatory cytokines and environmental stress.As an essential component of p38 MAP kinase mediated signal transduction pathway, this protein is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3275R-A680

Anti-MEK6 Ser207 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-3275R-A680)
Supplier: Bioss
Description: Mitogen activated protein kinase kinase 6 (MEK6 or MKK6) belongs to the serine/threonine protein kinase family and the MAPK kinase subfamily (MAP2K, MKK or MEKs). MEK6, closely related to MEK3, catalyses the concomitant phosphorylation of a threonine and a tyrosine residue in MAP kinase p38, thus activating it, in response to inflammatory cytokines and environmental stress.As an essential component of p38 MAP kinase mediated signal transduction pathway, this protein is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-15535R-A350

Anti-ICKTyr159 Rabbit Polyclonal Antibody (ALEXA FLUOR® 350)

Catalog Number: (BOSSBS-15535R-A350)
Supplier: Bioss
Description: Eukaryotic protein kinases are enzymes that belong to a very extensive family of proteins which share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases. This gene encodes an intestinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases. The protein localises to the intestinal crypt region and is thought to be important in intestinal epithelial cell proliferation and differentiation. Alternative splicing has been observed at this locus and two variants, encoding the same isoform, have been identified.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-15535R-A488

Anti-ICKTyr159 Rabbit Polyclonal Antibody (ALEXA FLUOR® 488)

Catalog Number: (BOSSBS-15535R-A488)
Supplier: Bioss
Description: Eukaryotic protein kinases are enzymes that belong to a very extensive family of proteins which share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases. This gene encodes an intestinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases. The protein localises to the intestinal crypt region and is thought to be important in intestinal epithelial cell proliferation and differentiation. Alternative splicing has been observed at this locus and two variants, encoding the same isoform, have been identified.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-15535R-A680

Anti-ICKTyr159 Rabbit Polyclonal Antibody (ALEXA FLUOR® 680)

Catalog Number: (BOSSBS-15535R-A680)
Supplier: Bioss
Description: Eukaryotic protein kinases are enzymes that belong to a very extensive family of proteins which share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases. This gene encodes an intestinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases. The protein localises to the intestinal crypt region and is thought to be important in intestinal epithelial cell proliferation and differentiation. Alternative splicing has been observed at this locus and two variants, encoding the same isoform, have been identified.
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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This product has been blocked by your organisation. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
Product(s) marked with this symbol are discontinued - sold till end of stock. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service on +353 1 8822222.
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