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Image Unavailable-BOSSBS-5545R-A555

Anti-PDPK1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-5545R-A555)
Supplier: Bioss
Description: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0223R-HRP

Anti-MAP2K2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-0223R-HRP)
Supplier: Bioss
Description: Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates the ERK1 and ERK2 MAP kinases (By similarity).
UOM: 1 * 100 µl
Image Unavailable-BWRLAP0484

Anti-p-ERK1/2 Rabbit Polyclonal Antibody [clone: T202/Y204]

Catalog Number: (BWRLAP0484)
Supplier: Bioworld Technology
Description: Synthetic phosphopeptide derived from human ERK1/2 around the phosphorylation site of Threonine 202/Tyrosine 204.
UOM: 1 * 100 µG
Image Unavailable-BOSSBS-3275R-A647

Anti-MAP2K6 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-3275R-A647)
Supplier: Bioss
Description: Mitogen activated protein kinase kinase 6 (MEK6 or MKK6) belongs to the serine/threonine protein kinase family and the MAPK kinase subfamily (MAP2K, MKK or MEKs). MEK6, closely related to MEK3, catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in MAP kinase p38, thus activating it, in response to inflammatory cytokines and environmental stress.As an essential component of p38 MAP kinase mediated signal transduction pathway, this protein is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-15536R

Anti-ICK Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-15536R)
Supplier: Bioss
Description: Eukaryotic protein kinases are enzymes that belong to a very extensive family of proteins which share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases. This gene encodes an intestinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases. The protein localizes to the intestinal crypt region and is thought to be important in intestinal epithelial cell proliferation and differentiation. Alternative splicing has been observed at this locus and two variants, encoding the same isoform, have been identified.
UOM: 1 * 100 µl
Product Image-ACRO125310010

(±)-Mandelic acid 99+%

Supplier: Thermo Fisher Scientific
Description: (±)-Mandelic acid 99+%

MSDS

Image Unavailable-BOSSBS-3392R

Anti-MAP2K4 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-3392R)
Supplier: Bioss
Description: This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. They form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues. A similar protein in mouse has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
UOM: 1 * 100 µl
Image Unavailable-8.19016.0100

(±)-Mandelonitrile for synthesis, Sigma-Aldrich®

Catalog Number: (8.19016.0100)
Supplier: Merck
Description: (±)-Mandelonitrile for synthesis, Sigma-Aldrich®
UOM: 1 * 100 mL

MSDS Certificates


Image Unavailable-BOSSBS-5545R-CY3

Anti-PDPK1 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-5545R-CY3)
Supplier: Bioss
Description: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.
UOM: 1 * 100 µl
Image Unavailable-BWRLBS4457

Anti-p-AMPKalpha1/2 Rabbit Polyclonal Antibody [clone: T183/172]

Catalog Number: (BWRLBS4457)
Supplier: Bioworld Technology
Description: Synthetic phosphopeptide derived from human AMPKalpha1 around the phosphorylation site of Threonine 183.
UOM: 1 * 100 µG
Image Unavailable-BOSSBS-3535R-A680

Anti-PLK1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-3535R-A680)
Supplier: Bioss
Description: PLK1 (polo-like kinase 1) is a member of the serine/threonine protein kinase family, cdc5/polo subfamily. PLK1 contains two polo box domains with a predicted molecular weight of 68 kDa. PLK1 has been shown to regulate cdc2/cyclin B through phosphorylation and activation of cdc25c phosphatase. PLK1 is modified by phosphorylation at Threonine 210. PLK1 may also be required for cell division. Depletion of PLK1 results in apoptosis and deregulation of expression of PKL1 is correlated with development of many malignancies.
UOM: 1 * 100 µl
Image Unavailable-BWRLAP0291

Anti-p-PKC delta Rabbit Polyclonal Antibody [clone: T505]

Catalog Number: (BWRLAP0291)
Supplier: Bioworld Technology
Description: Synthetic phosphopeptide derived from human PKC delta around the phosphorylation site of Threonine 505.
UOM: 1 * 100 µG
Image Unavailable-BWRLBS4347

Anti-p-PKC zeta Rabbit Polyclonal Antibody [clone: T560]

Catalog Number: (BWRLBS4347)
Supplier: Bioworld Technology
Description: Synthetic phosphopeptide derived from human PKC zeta around the phosphorylation site of Threonine 560.
UOM: 1 * 100 µG
Image Unavailable-BOSSBS-15535R-HRP

Anti-ICKTyr159 Rabbit Polyclonal Antibody (HRP)

Catalog Number: (BOSSBS-15535R-HRP)
Supplier: Bioss
Description: Eukaryotic protein kinases are enzymes that belong to a very extensive family of proteins which share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases. This gene encodes an intestinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases. The protein localises to the intestinal crypt region and is thought to be important in intestinal epithelial cell proliferation and differentiation. Alternative splicing has been observed at this locus and two variants, encoding the same isoform, have been identified.
UOM: 1 * 100 µl
Image Unavailable-SPCMT1056-25GM

L-Threonine ≥98.5%, crystals USP

Catalog Number: (SPCMT1056-25GM)
Supplier: Spectrum Chemical
Description: Threonine, Crystal, USP is an amino acid that is used in the biosynthesis of proteins. 
UOM: 1 * 25 g

Certificates


Image Unavailable-BOSSBS-3535R-A488

Anti-PLK1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-3535R-A488)
Supplier: Bioss
Description: PLK1 (polo-like kinase 1) is a member of the serine/threonine protein kinase family, cdc5/polo subfamily. PLK1 contains two polo box domains with a predicted molecular weight of 68 kDa. PLK1 has been shown to regulate cdc2/cyclin B through phosphorylation and activation of cdc25c phosphatase. PLK1 is modified by phosphorylation at Threonine 210. PLK1 may also be required for cell division. Depletion of PLK1 results in apoptosis and deregulation of expression of PKL1 is correlated with development of many malignancies.
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us on +353 1 88 22222.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at eurega_services@eu.vwr.com
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